Literature DB >> 705015

Detection and assay of antitumor antibiotics.

L J Hanka, S L Kuentzel, D G Martin, P F Wiley, G L Neil.   

Abstract

Cell culture techniques and antimicrobial systems can be used as detection systems for new antibiotic structures. Antimicrobial systems by virtue of their speed, economy, ease of use, and adaptation to chromatographic (bioautographic) techniques are definitely superior for assay and for dereplication purposes. A prescreen assay system which combines the advantages and minimizes the disadvantages of the two approaches is described.

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Year:  1978        PMID： 705015     DOI： 10.1007/978-3-642-81219-4_7

Source DB:  PubMed          Journal:  Recent Results Cancer Res        ISSN： 0080-0015


  3 in total

Review 1.  Current status and contemporary approaches to the discovery of antitumor agents from higher plants.

Authors:  Garima Agarwal; Peter J Blanco Carcache; Ermias Mekuria Addo; A Douglas Kinghorn
Journal:  Biotechnol Adv       Date:  2019-01-08       Impact factor: 14.227

2.  Bioactive compound production by thermophilic and thermotolerant cyanobacteria (blue-green algae).

Authors:  S A Fish; G A Codd
Journal:  World J Microbiol Biotechnol       Date:  1994-05       Impact factor: 3.312

3.  Improved genetically modified Escherichia coli strain for prescreening antineoplastic agents.

Authors:  H R Bartus; C K Mirabelli; J I Auerbach; A R Shatzman; D P Taylor; R K Johnson; M Rosenberg; S T Crooke
Journal:  Antimicrob Agents Chemother       Date:  1984-05       Impact factor: 5.191
  3 in total

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