Literature DB >> 7049293

Does tryptophan potentiate clomipramine in the treatment of agoraphobic and social phobic patients?

J C Pecknold, D J McClure, L Appeltauer, T Allan, L Wrzesinski.   

Abstract

A 10 week double blind study of 24 agoraphobics and 16 social phobics all on clomipramine compared the effect of adding tryptophan or placebo. Tryptophan did not potentiate the beneficial effect of clomipramine on phobic avoidance, phobic fears or the incidence of panic attacks. Neither was the presence of depression a factor of outcome.

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Year:  1982        PMID： 7049293     DOI： 10.1192/bjp.140.5.484

Source DB:  PubMed          Journal:  Br J Psychiatry        ISSN： 0007-1250            Impact factor:   9.319


  8 in total

1.  Behavioral, biochemical, and blood pressure responses to alprazolam in healthy subjects: interactions with yohimbine.

Authors:  D S Charney; A Breier; P I Jatlow; G R Heninger
Journal:  Psychopharmacology (Berl)       Date:  1986       Impact factor: 4.530

Review 2.  A risk-benefit assessment of buspirone in the treatment of anxiety disorders.

Authors:  J C Pecknold
Journal:  Drug Saf       Date:  1997-02       Impact factor: 5.606

Review 3.  Clomipramine. An overview of its pharmacological properties and a review of its therapeutic use in obsessive compulsive disorder and panic disorder.

Authors:  D McTavish; P Benfield
Journal:  Drugs       Date:  1990-01       Impact factor: 9.546

Review 4.  Recent developments in the psychopharmacology of social phobia.

Authors:  J A Den Boer; I M van Vliet; H G Westenberg
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  1995       Impact factor: 5.270

5.  Fluoxetine in panic disorder: pharmacologic and tritiated platelet imipramine and paroxetine binding study.

Authors:  J C Pecknold; L Luthe; L Iny; D Ramdoyal
Journal:  J Psychiatry Neurosci       Date:  1995-05       Impact factor: 6.186

6.  Psychopharmacological treatment of social phobia; a double blind placebo controlled study with fluvoxamine.

Authors:  I M van Vliet; J A den Boer; H G Westenberg
Journal:  Psychopharmacology (Berl)       Date:  1994-06       Impact factor: 4.530

7.  Tryptophan research in panic disorder.

Authors:  Eduard Maron; Jakov Shlik; David J Nutt
Journal:  Int J Tryptophan Res       Date:  2008-08-14

Review 8.  Pharmacotherapy for social anxiety disorder (SAnD).

Authors:  Taryn Williams; Coenraad J Hattingh; Catherine M Kariuki; Sean A Tromp; Anton J van Balkom; Jonathan C Ipser; Dan J Stein
Journal:  Cochrane Database Syst Rev       Date:  2017-10-19
  8 in total

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