Literature DB >> 7049074

Assay of netilmicin, using enzyme immunoassay for gentamicin.

T Larson, D N Gerding, L R Peterson, J H Eckfeldt.   

Abstract

A homogenous enzyme immunoassay for the quantitative determination of netilmicin in serum was developed. The procedure utilizes a commercially available assay for gentamicin (EMIT; Syva Co., Palo Alto, Calif.). The method was adapted to a microcentrifugal analyzer, and log-logit regression analysis was performed with a computer. The results of samples assayed by this method correlate well with microbioassay (r2 = 0.985) and radioimmunoassay (r2 = 0.986). This method is not only precise and accurate, but also very rapid and economical and compares favorably to other available methods of netilmicin assay.

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Year:  1982        PMID： 7049074      PMCID： PMC181903          DOI： 10.1128/AAC.21.3.399

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  14 in total

1.  Radioimmunoassay of sisomicin.

Authors:  A Broughton; J E Strong; G P Bodey
Journal:  Antimicrob Agents Chemother       Date:  1976-02       Impact factor: 5.191

2.  Antibacterial activity of netilmicin, a new aminoglycoside antibiotic, compared with that of gentamicin.

Authors:  I Phillips; A Smith; K Shannon
Journal:  Antimicrob Agents Chemother       Date:  1977-03       Impact factor: 5.191

3.  In vitro activity of netilmicin.

Authors:  J A Smith; J R Morgan; M Mogyoros
Journal:  Antimicrob Agents Chemother       Date:  1977-02       Impact factor: 5.191

4.  Evaluation of five gentamicin assay procedures for clinical microbiology laboratories.

Authors:  S T Selepak; F G Witebsky; E A Robertson; J D MacLowry
Journal:  J Clin Microbiol       Date:  1981-04       Impact factor: 5.948

5.  Comparison of five methods for the assay of serum gentamicin.

Authors:  R M Ratcliff; C Mirelli; E Moran; D O'Leary; R White
Journal:  Antimicrob Agents Chemother       Date:  1981-04       Impact factor: 5.191

6.  Disc plate method of microbiological antibiotic assay. I. Factors influencing variability and error.

Authors:  W W Davis; T R Stout
Journal:  Appl Microbiol       Date:  1971-10

7.  Comparative nephrotoxicities of netilmicin and gentamicin in rats.

Authors:  F C Luft; M N Yum; S A Kleit
Journal:  Antimicrob Agents Chemother       Date:  1976-11       Impact factor: 5.191

8.  Antimicrobial activity in vitro of netilmicin and comparison with sisomicin, gentamicin, and tobramycin.

Authors:  B R Meyers; S Z Hirschman
Journal:  Antimicrob Agents Chemother       Date:  1977-01       Impact factor: 5.191

9.  In vitro activity of netilmicin, gentamicin, and amikacin.

Authors:  R J Kantor; C W Norden
Journal:  Antimicrob Agents Chemother       Date:  1977-01       Impact factor: 5.191

10.  Netilmicin and gentamicin: comparative pharmacology in humans.

Authors:  L J Riff; G Moreschi
Journal:  Antimicrob Agents Chemother       Date:  1977-04       Impact factor: 5.191
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  4 in total

1.  Evaluation of five immunological methods for the assay of serum netilmicin.

Authors:  C Van Remmerden; J R Brouwers; J A Berk; R J Boskma
Journal:  Pharm Weekbl Sci       Date:  1984-04-27

2.  Evaluation of new blood culture processing systems.

Authors:  J A Moody; C E Fasching; C J Shanholtzer; D N Gerding; L R Peterson
Journal:  J Clin Microbiol       Date:  1984-09       Impact factor: 5.948

3.  Comparison of azlocillin, ceftizoxime, cefoxitin, and amikacin alone and in combination against Pseudomonas aeruginosa in a neutropenic-site rabbit model.

Authors:  L R Peterson; D N Gerding; J A Moody; C E Fasching
Journal:  Antimicrob Agents Chemother       Date:  1984-05       Impact factor: 5.191

Review 4.  Netilmicin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

Authors:  D M Campoli-Richards; S Chaplin; R H Sayce; K L Goa
Journal:  Drugs       Date:  1989-11       Impact factor: 9.546
  4 in total

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