Literature DB >> 7048142

Effects of optical isomers of ketamine on excitation of cat and rat spinal neurones by amino acids and acetylcholine.

D Lodge, N A Anis, N R Burton.   

Abstract

The (+) isomer of ketamine was approximately 3 and 1.5 times as potent as the (-) isomer in reducing excitation of rat and cat Renshaw cells by N-methylaspartate (NMA) and acetylcholine (ACh) respectively. The potency ratio of the two isomers of ketamine as NMA antagonists was similar to that obtained in anaesthetic and analgesic tests [16, 19, 25].

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Year:  1982        PMID： 7048142     DOI： 10.1016/0304-3940(82)90330-5

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  19 in total

Review 1.  General anaesthetic actions on ligand-gated ion channels.

Authors:  M D Krasowski; N L Harrison
Journal:  Cell Mol Life Sci       Date:  1999-08-15       Impact factor: 9.261

Review 2.  Ketamine for treatment-resistant unipolar depression: current evidence.

Authors:  Sanjay J Mathew; Asim Shah; Kyle Lapidus; Crystal Clark; Noor Jarun; Britta Ostermeyer; James W Murrough
Journal:  CNS Drugs       Date:  2012-03-01       Impact factor: 5.749

3.  K+ channels in PC12 cells are affected by propofol.

Authors:  V Magnelli; M Nobile; E Maestrone
Journal:  Pflugers Arch       Date:  1992-03       Impact factor: 3.657

4.  Downregulated kynurenine 3-monooxygenase gene expression and enzyme activity in schizophrenia and genetic association with schizophrenia endophenotypes.

Authors:  Ikwunga Wonodi; O Colin Stine; Korrapati V Sathyasaikumar; Rosalinda C Roberts; Braxton D Mitchell; L Elliot Hong; Yasushi Kajii; Gunvant K Thaker; Robert Schwarcz
Journal:  Arch Gen Psychiatry       Date:  2011-07

Review 5.  Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms.

Authors:  Panos Zanos; Ruin Moaddel; Patrick J Morris; Lace M Riggs; Jaclyn N Highland; Polymnia Georgiou; Edna F R Pereira; Edson X Albuquerque; Craig J Thomas; Carlos A Zarate; Todd D Gould
Journal:  Pharmacol Rev       Date:  2018-07       Impact factor: 25.468

Review 6.  Circuits and functions of the lateral habenula in health and in disease.

Authors:  Hailan Hu; Yihui Cui; Yan Yang
Journal:  Nat Rev Neurosci       Date:  2020-04-08       Impact factor: 34.870

Review 7.  Hydroxynorketamines: Pharmacology and Potential Therapeutic Applications.

Authors:  Jaclyn N Highland; Panos Zanos; Lace M Riggs; Polymnia Georgiou; Sarah M Clark; Patrick J Morris; Ruin Moaddel; Craig J Thomas; Carlos A Zarate; Edna F R Pereira; Todd D Gould
Journal:  Pharmacol Rev       Date:  2021-04       Impact factor: 25.468

Review 8.  Risks Associated with Misuse of Ketamine as a Rapid-Acting Antidepressant.

Authors:  Weili Zhu; Zengbo Ding; Yinan Zhang; Jie Shi; Kenji Hashimoto; Lin Lu
Journal:  Neurosci Bull       Date:  2016-11-22       Impact factor: 5.203

9.  Interactions of some anaesthetic, convulsant, and anticonvulsant drugs at GABA-benzodiazepine receptor-ionophore complexes in rat brain synaptosomal membranes.

Authors:  J H Skerritt; G A Johnston
Journal:  Neurochem Res       Date:  1983-10       Impact factor: 3.996

Review 10.  Ketamine use in current clinical practice.

Authors:  Mei Gao; Damoon Rejaei; Hong Liu
Journal:  Acta Pharmacol Sin       Date:  2016-03-28       Impact factor: 6.150
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