| Literature DB >> 7047281 |
V V Dolgov, O E Zaikina, M F Bondarenko, V S Repin.
Abstract
Scanning electron microscope studies of the aorta and other major arteries have been performed in alloxan-induced diabetic rabbits. After 5 weeks, a variety of structural abnormalities of the endothelial lining were detected including a significant increase in the number of argyrophilic cells and an increased number of craters or openings in the endothelial junctional region. Evidence of more extensive micro-damage was present after 5 months duration of diabetes. These zones with structural changes in the endothelial lining of major vessels seem to be areas of high predilection to atherosclerosis in diabetes.Entities:
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Year: 1982 PMID: 7047281 DOI: 10.1007/bf00253578
Source DB: PubMed Journal: Diabetologia ISSN: 0012-186X Impact factor: 10.122