Literature DB >> 7046738

The effects of orthovanadate on fatty acid synthesis in isolated rat hepatocytes.

L Agius, W J Vaartjes.   

Abstract

Extracellular Ca2+ stimulated fatty acid synthesis in isolated rat hepatocytes. Orthovanadate (0.2--2.0 mM), an inhibitor of Ca2+-dependent ATPases, stimulated fatty acid synthesis in both the presence and the absence of extracellular Ca2+. Insulin stimulated fatty acid synthesis only in the presence of extracellular Ca2+. The contribution of extracellular Ca2+ to insulin stimulation of fatty acid synthesis is discussed.

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Year:  1982        PMID： 7046738      PMCID： PMC1158177          DOI： 10.1042/bj2020791

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  24 in total

1.  Acute effects in vivo of anti-insulin serum on rates of fatty acid synthesis and activities of acetyl-coenzyme A carboxylase and pyruvate dehydrogenase in liver and epididymal adipose tissue of fed rats.

Authors:  D Stansbie; R W Brownsey; M Crettaz; R M Denton
Journal:  Biochem J       Date:  1976-11-15       Impact factor: 3.857

2.  Studies on the inhibition of hepatic lipogenesis by N-6,O-2'-dibutyryl adenosine 3',5'-monophosphate.

Authors:  R A Harris
Journal:  Arch Biochem Biophys       Date:  1975-07       Impact factor: 4.013

3.  Secretory processes, carbohydrate and lipid metabolism in isolated mouse hepatocytes. Aspects of regulation by glucagon and insulin.

Authors:  P Müller; A Singh; L Orci; B Jeanrenaud
Journal:  Biochim Biophys Acta       Date:  1976-04-23

Review 4.  Preparation of isolated rat liver cells.

Authors:  P O Seglen
Journal:  Methods Cell Biol       Date:  1976       Impact factor: 1.441

5.  Role of extracellular calcium in the action of vasopressin on hepatic glycogenolysis.

Authors:  M Stubbs; C J Kirk; D A Hems
Journal:  FEBS Lett       Date:  1976-10-15       Impact factor: 4.124

6.  The effects of divalent cations and insulin on protein synthesis in adipose cells.

Authors:  B O Jacobs; M E Krahl
Journal:  Biochim Biophys Acta       Date:  1973-09-07

7.  Fatty acid synthesis in adipose tissue incubated in tritiated water.

Authors:  R L Jungas
Journal:  Biochemistry       Date:  1968-10       Impact factor: 3.162

8.  Cyclic guanosine 3':5'-monophosphate and the regulation of lipolysis in rat fat cells.

Authors:  J N Fain; F R Butcher
Journal:  J Cyclic Nucleotide Res       Date:  1976

9.  Metabolic actions of vasopressin, glucagon and adrenalin in the intact rat.

Authors:  D A Hems; P D Whitton; G Y Ma
Journal:  Biochim Biophys Acta       Date:  1975-11-10

10.  Vanadate is a potent (Na,K)-ATPase inhibitor found in ATP derived from muscle.

Authors:  L C Cantley; L Josephson; R Warner; M Yanagisawa; C Lechene; G Guidotti
Journal:  J Biol Chem       Date:  1977-11-10       Impact factor: 5.157
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  8 in total

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2.  Monolayer culture of parenchymal rat hepatocytes on collagen-coated microcarriers. A hepatocyte system for short- and long-term metabolic studies.

Authors:  L Agius; C Battersby; K G Alberti
Journal:  In Vitro Cell Dev Biol       Date:  1985-05

3.  Biological effects of sulphated insulin in adipocytes and hepatocytes.

Authors:  S Zeuzem; R Taylor; L Agius; K Schoeffling; A M Albisser; K G Alberti
Journal:  Mol Cell Biochem       Date:  1985-10       Impact factor: 3.396

Review 4.  Metabolic and molecular action of Trigonella foenum-graecum (fenugreek) and trace metals in experimental diabetic tissues.

Authors:  Najma Zaheer Baquer; Pardeep Kumar; Asia Taha; R K Kale; S M Cowsik; P McLean
Journal:  J Biosci       Date:  2011-06       Impact factor: 1.826

5.  Effects of sodium-orthovanadate and Trigonella foenum-graecum seeds on hepatic and renal lipogenic enzymes and lipid profile during alloxan diabetes.

Authors:  Umesh C S Yadav; K Moorthy; Najma Z Baquer
Journal:  J Biosci       Date:  2004-03       Impact factor: 1.826

6.  Carriers for abscisic acid and indole-3-acetic acid in primary roots: their regional localisation and thermodynamic driving forces.

Authors:  M C Astle; P H Rubery
Journal:  Planta       Date:  1983-02       Impact factor: 4.116

7.  Regulation of ketogenesis, gluconeogenesis and the mitochondrial redox state by dexamethasone in hepatocyte monolayer cultures.

Authors:  L Agius; M H Chowdhury; K G Alberti
Journal:  Biochem J       Date:  1986-11-01       Impact factor: 3.857

8.  Tissue-specific correction of lipogenic enzyme gene expression in diabetic rats given vanadate.

Authors:  S M Brichard; L N Ongemba; J Girard; J C Henquin
Journal:  Diabetologia       Date:  1994-11       Impact factor: 10.122
  8 in total

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