| Literature DB >> 7044813 |
P Tortora, N Burlini, G M Hanozet, A Guerritore.
Abstract
Activity of yeast glucose-6-phosphate dehydrogenase, inactivated by treatment with saturated fatty acids, can be partially restored by incubation in a medium of suitable ionic composition. The effectiveness of ions in the reactivation process is inversely related to their 'chaotropic' properties. Time-dependence of reactivation extent suggests a 2-step mechanism of enzyme inactivation and the existence of an intermediate form that aggregates through a 2nd-order reaction, producing irreversibly inactive enzyme.Entities:
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Year: 1982 PMID: 7044813 DOI: 10.1007/bf01952620
Source DB: PubMed Journal: Experientia ISSN: 0014-4754