Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Histopathological and laboratory assessment of visual dysfunction.

Literature DB >> 7044774

Histopathological and laboratory assessment of visual dysfunction.

Abstract

The currently available methods of assessing ocular toxicity are discussed. Manifestations of ocular toxicity are best described clinically; histopathological examination of the eye is beset with problems of preparing the eye for morphological examinations. Electron microscopy is essential to look for chemically induced side effects at the cellular level. Mechanisms of ocular toxicity are poorly understood, and the limitation of animal studies in predicting side effects in man must be appreciated.

Entities: Disease Species

Mesh：

Year: 1982 PMID： 7044774 PMCID： PMC1568961 DOI： 10.1289/ehp.824435

Source DB: PubMed Journal: Environ Health Perspect ISSN： 0091-6765 Impact factor: 9.031

30 in total

2. Pathogenesis and reversibility of retinopathy induced by 1,4-bis (4-aminophenoxy)-2-phenylbenzene (2-phenyl-APB-144) in pigmented rats.

Authors: K P Lee; R Valentine
Journal: Arch Toxicol Date: 1991 Impact factor: 5.153

2 in total

Histopathological and laboratory assessment of visual dysfunction.

1. ERG responses of rods and cones during dark adaptation.

2. Pigment epithelial windows and drusen: an animal model.

3. Notes on Technique for Postmortem Examination of the Eye.

4. [Modification of color vision caused by use of normal therapeutic doses of certain drugs].

5. Occurrence of corneal opacities in rats after acute administration of l-alpha-acetylmethadol.

6. Chloroquine retinopathy in the rhesus monkey.

7. Histopathology of experimental ethambutol intoxication.

8. Ocular effects in dogs and pigs treated with dichloran (2,6-dichloro-4-nitroaniline).

9. Chromodacryorrhea in laboratory rats (Rattus norvegicus): etiologic considerations.

10. Pulmonary changes induced by amphophilic drugs.

1. Retinotoxicity of 1,4,-bis(4-aminophenoxy)-2-phenylbenzene (2-phenyl-APB-144) in albino and pigmented rats.

2. Pathogenesis and reversibility of retinopathy induced by 1,4-bis (4-aminophenoxy)-2-phenylbenzene (2-phenyl-APB-144) in pigmented rats.