Literature DB >> 7044412

Double-masked controlled clinical trial of 5% tolmetin versus 0.5% prednisolone versus 0.9% saline in acute endogenous nongranulomatous anterior uveitis.

B J Young, W F Cunningham, T Akingbehin.   

Abstract

A double-masked controlled clinical trial of 5% unpreserved tolmetin versus 0.5% prednisolone versus 0.9% saline in acute endogenous nongranulomatous anterior uveitis was carried out on 100 patients. 69% of the prednisolone-treated patients were judged "cured" at the end of the 3-week study. This is compared with a cure rate of 47% for the tolmetin-treated patients for 53% for the placebo (saline) group. No statistically significant difference was established between the 3 groups.

Entities:  

Mesh:

Substances:

Year:  1982        PMID: 7044412      PMCID: PMC1039806          DOI: 10.1136/bjo.66.6.389

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  18 in total

1.  INTRAOCULAR PRESSURE RESPONSE TO TOPICAL CORTICOSTEROIDS.

Authors:  B BECKER
Journal:  Invest Ophthalmol       Date:  1965-04

2.  Corneal infections after cortisone therapy.

Authors:  Y MITSUI; J HANABUSA
Journal:  Br J Ophthalmol       Date:  1955-04       Impact factor: 4.638

3.  Cortisone glaucoma.

Authors:  H GOLDMANN
Journal:  Arch Ophthalmol       Date:  1962-11

Review 4.  Tolmetin: a review of its pharmacological properties and therapeutic efficacy in rheumatic diseases.

Authors:  R N Brogden; R C Heel; T M Speight; G S Avery
Journal:  Drugs       Date:  1978-06       Impact factor: 9.546

Review 5.  Acute anterior uveitis and prostaglandins.

Authors:  R A Whitelocke; K E Eakins; A Bennett
Journal:  Proc R Soc Med       Date:  1973-05

Review 6.  Noncorticosteroidal anti-inflammatory agents in Ophthalmology.

Authors:  I H Leopold; D Murray
Journal:  Ophthalmology       Date:  1979-01       Impact factor: 12.079

Review 7.  Direct fungal infection of the eye in Britain.

Authors:  B R Jones; A B Richards; G Morgan
Journal:  Trans Ophthalmol Soc U K       Date:  1970

8.  Aspirin stabilization of the blood-aqueous barrier in the human eye.

Authors:  T J Zimmerman; N Gravenstein; A Sugar; H E Kaufman
Journal:  Am J Ophthalmol       Date:  1975-05       Impact factor: 5.258

9.  Prostaglandins, nonsteroidal anti-inflammatory agents and eye disease.

Authors:  S M Podos
Journal:  Trans Am Ophthalmol Soc       Date:  1976

10.  Prostaglandin-like activity in ocular inflammation.

Authors:  K E Eakins; R A Whitelocke; A Bennett; A C Martenet
Journal:  Br Med J       Date:  1972-08-19
View more
  6 in total

Review 1.  Uveitis (acute anterior).

Authors:  Niaz Islam; Carlos Pavesio
Journal:  BMJ Clin Evid       Date:  2010-04-08

2.  Double-blind controlled trial to compare anti-inflammatory effects of tolmetin 2%, prednisolone 0.5%, and placebo in post-cataract extraction eyes.

Authors:  D L Smerdon; S O Hung; T Akingbehin
Journal:  Br J Ophthalmol       Date:  1986-10       Impact factor: 4.638

Review 3.  Evidence-based, interdisciplinary guidelines for anti-inflammatory treatment of uveitis associated with juvenile idiopathic arthritis.

Authors:  A Heiligenhaus; H Michels; C Schumacher; I Kopp; U Neudorf; T Niehues; H Baus; M Becker; B Bertram; G Dannecker; C Deuter; I Foeldvari; M Frosch; G Ganser; M Gaubitz; G Gerdes; G Horneff; A Illhardt; F Mackensen; K Minden; U Pleyer; M Schneider; N Wagner; M Zierhut
Journal:  Rheumatol Int       Date:  2011-11-15       Impact factor: 2.631

Review 4.  [Uveitis in conjunction with rheumatological diseases in childhood].

Authors:  C Sengler; R Keitzer; U Pleyer
Journal:  Ophthalmologe       Date:  2005-05       Impact factor: 1.059

Review 5.  Is ophthalmology evidence based? A clinical audit of the emergency unit of a regional eye hospital.

Authors:  T Y Y Lai; V W Y Wong; G M Leung
Journal:  Br J Ophthalmol       Date:  2003-04       Impact factor: 4.638

6.  Efficacy in anterior uveitis of two known steroids and topical tolmetin.

Authors:  J A Dunne; N Jacobs; A Morrison; D J Gilbert
Journal:  Br J Ophthalmol       Date:  1985-02       Impact factor: 4.638

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.