Literature DB >> 7044041

Monocyte functions in diabetes mellitus.

C Geisler, T Almdal, J Bennedsen, J M Rhodes, K Kølendorf.   

Abstract

The aim of this study was to investigate the functions of monocytes obtained from 14 patients with diabetes mellitus (DM) compared with those of monocytes from healthy individuals. It was found that the total number of circulating monocytes in the 14 diabetic patients was lower than that from the healthy individuals. Phagocytosis of Candida albicans was decreased in the monocytes from the patients, whereas pinocytosis of acridine and phagocytosis of latex and sheep red blood cells were normal. The chemotactic response towards casein was enhanced. The possible consequences of these findings for the elucidation of concomitant infections in diabetic patients are discussed.

Entities:  

Mesh：

Year:  1982        PMID： 7044041     DOI： 10.1111/j.1699-0463.1982.tb01414.x

Source DB:  PubMed          Journal:  Acta Pathol Microbiol Immunol Scand C        ISSN： 0108-0202


  8 in total

1.  Elevated glucose concentrations promote receptor-independent activation of adherent human neutrophils: an experimental and computational approach.

Authors:  Ursula Kummer; Jürgen Zobeley; Jens Christian Brasen; Ryan Fahmy; Andrei L Kindzelskii; Aaron R Petty; Andrea J Clark; Howard R Petty
Journal:  Biophys J       Date:  2007-01-19       Impact factor: 4.033

2.  Thiol oxidative stress induced by metabolic disorders amplifies macrophage chemotactic responses and accelerates atherogenesis and kidney injury in LDL receptor-deficient mice.

Authors:  Mu Qiao; Qingwei Zhao; Chi Fung Lee; Lisa R Tannock; Eric J Smart; Richard G LeBaron; Clyde F Phelix; Yolanda Rangel; Reto Asmis
Journal:  Arterioscler Thromb Vasc Biol       Date:  2009-07-10       Impact factor: 8.311

3.  Circulating monocytes are activated in newly diagnosed type 1 diabetes mellitus patients.

Authors:  K Josefsen; H Nielsen; S Lorentzen; P Damsbo; K Buschard
Journal:  Clin Exp Immunol       Date:  1994-12       Impact factor: 4.330

Review 4.  The impact of diabetes on the pathogenesis of sepsis.

Authors:  G C K W Koh; S J Peacock; T van der Poll; W J Wiersinga
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2011-07-30       Impact factor: 3.267

5.  Phagocytic activity is impaired in type 2 diabetes mellitus and increases after metabolic improvement.

Authors:  Albert Lecube; Gisela Pachón; Jordi Petriz; Cristina Hernández; Rafael Simó
Journal:  PLoS One       Date:  2011-08-18       Impact factor: 3.240

6.  Phagocytosis via complement or Fc-gamma receptors is compromised in monocytes from type 2 diabetes patients with chronic hyperglycemia.

Authors:  Blanca I Restrepo; Marcel Twahirwa; Mohammad H Rahbar; Larry S Schlesinger
Journal:  PLoS One       Date:  2014-03-26       Impact factor: 3.240

7.  CD14+ monocytes are vulnerable and functionally impaired under endoplasmic reticulum stress in patients with type 2 diabetes.

Authors:  Takuya Komura; Yoshio Sakai; Masao Honda; Toshinari Takamura; Kouji Matsushima; Shuichi Kaneko
Journal:  Diabetes       Date:  2009-12-03       Impact factor: 9.461

8.  Reduced Mycobacterium tuberculosis association with monocytes from diabetes patients that have poor glucose control.

Authors:  Diana I Gomez; Marcel Twahirwa; Larry S Schlesinger; Blanca I Restrepo
Journal:  Tuberculosis (Edinb)       Date:  2012-11-03       Impact factor: 2.973
  8 in total

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