Literature DB >> 7043858

[Automatic cytodiagnostic of bladder cancer (author's transl)].

A Zimmermann.   

Abstract

Searching for bladder cancer, 1268 flow-through-cytophotometric determinations of DNA in nuclei of cells were done using the ICP 11. 134 urines (36.2%) and 15 bladder washings (2.9%) could not be evaluated. The examination of urines led to a right positive diagnosis in 56.7%. The corresponding values in wash-out material and biopsy specimen were 61.2% and 75.3%. False positive results were found of 32.5% of the urines, 6.2% of the wash-out fluid and 9.1% in the biopsy specimens. The results are slightly less advantageous than those of conventional cytodiagnostic. Using a special way in selecting the results, false positive values could be eliminated. By this the tentative diagnosis of cancer gained by flow-through-cytophotometry, could be estimated to be correct in a high percentage. It seems that the flow-through-cytophotometry carried out as additional morphological test is an improvement in diagnosis and grading as well as in estimating prognosis and therapeutic results of urological cancer.

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Year:  1982        PMID: 7043858

Source DB:  PubMed          Journal:  Urologe A        ISSN: 0340-2592            Impact factor:   0.639


  1 in total

1.  Microcalorimetric measurements carried out on isolated tumorous and nontumorous tissue samples from organs in the urogenital tract in comparison to histological and impulse-cytophotometric investigations.

Authors:  M Kallerhoff; M Karnebogen; D Singer; A Dettenbach; U Gralher; R H Ringert
Journal:  Urol Res       Date:  1996
  1 in total

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