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Literature DB >> 7042762

Polyvalent heat-killed antigen for the diagnosis of infection with Legionella pneumophila.

Abstract

A polyvalent antigen composed of heat-killed agar-grown Legionella pneumophila serogroups 1-4 suspended in a suspension of yolk-sac from embryonated hens' eggs has been examined for use in the indirect fluorescent antibody test for Legionella infection. The serological response detected by monovalent antigen correlated well with that detected by polyvalent antigen. The use of polyvalent antigen forms a useful screening test for the detection of antibody to L pneumophila, but positive results must be confirmed by test using monovalent antigen.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1982 PMID： 7042762 PMCID： PMC497676 DOI： 10.1136/jcp.35.4.434

Source DB: PubMed Journal: J Clin Pathol ISSN： 0021-9746 Impact factor: 3.411

13 in total

1. Improved mountant for immunofluorescence preparations.

Authors: G V Heimer; C E Taylor
Journal: J Clin Pathol Date: 1974-03 Impact factor: 3.411

2. Measure of immunoglobulin G-, M-, and A-specific titers against Legionella pneumophila and inhibition of titers against nonspecific, gram-negative bacterial antigens in the indirect immunofluorescence test for legionellosis.

Authors: H W Wilkinson; C E Farshy; B J Fikes; D D Cruce; L P Yealy
Journal: J Clin Microbiol Date: 1979-11 Impact factor: 5.948

3. Detecting legionnaires' disease.

Authors: R J Fallon; W H Abraham
Journal: Lancet Date: 1978-12-16 Impact factor: 79.321

4. Four serogroups of Legionnaires' disease bacteria defined by direct immunofluorescence.

Authors: R M McKinney; L Thacker; P P Harris; K R Lewallen; G A Hebert; P H Edelstein; B M Thomason
Journal: Ann Intern Med Date: 1979-04 Impact factor: 25.391

5. False positive reactions in the indirect fluorescent antibody test for Legionnaires' disease eliminated by use of formolised yolk-sac antigen.

Authors: A G Taylor; T G Harrison; M W Dighero; C M Bradstreet
Journal: Ann Intern Med Date: 1979-04 Impact factor: 25.391

6. Recognition of a new serogroup of Legionnaires disease bacterium.

Authors: R M McKinney; B M Thomason; P P Harris; L Thacker; K R Lewallen; H W Wilkinson; G A Hebert; C W Moss
Journal: J Clin Microbiol Date: 1979-01 Impact factor: 5.948

7. Scottish experience with the serologic diagnosis of Legionnaires' disease.

Authors: R J Fallon; W H Abraham
Journal: Ann Intern Med Date: 1979-04 Impact factor: 25.391

8. Legionnaires' disease: isolation of a bacterium and demonstration of its role in other respiratory disease.

Authors: J E McDade; C C Shepard; D W Fraser; T R Tsai; M A Redus; W R Dowdle
Journal: N Engl J Med Date: 1977-12-01 Impact factor: 91.245

9. Indirect immunofluorescence test for serodiagnosis of Legionnaires disease: evidence for serogroup diversity of Legionnaires disease bacterial antigens and for multiple specificity of human antibodies.

Authors: H W Wilkinson; B J Fikes; D D Cruce
Journal: J Clin Microbiol Date: 1979-03 Impact factor: 5.948

Polyvalent heat-killed antigen for the diagnosis of infection with Legionella pneumophila.

1. Improved mountant for immunofluorescence preparations.

2. Measure of immunoglobulin G-, M-, and A-specific titers against Legionella pneumophila and inhibition of titers against nonspecific, gram-negative bacterial antigens in the indirect immunofluorescence test for legionellosis.

3. Detecting legionnaires' disease.

4. Four serogroups of Legionnaires' disease bacteria defined by direct immunofluorescence.

5. False positive reactions in the indirect fluorescent antibody test for Legionnaires' disease eliminated by use of formolised yolk-sac antigen.

6. Recognition of a new serogroup of Legionnaires disease bacterium.

7. Scottish experience with the serologic diagnosis of Legionnaires' disease.

8. Legionnaires' disease: isolation of a bacterium and demonstration of its role in other respiratory disease.

9. Indirect immunofluorescence test for serodiagnosis of Legionnaires disease: evidence for serogroup diversity of Legionnaires disease bacterial antigens and for multiple specificity of human antibodies.

10. Charcoal-yeast extract agar: primary isolation medium for Legionella pneumophila.

1. Variation in time and space of non-outbreak Legionnaires' disease in Scotland.

2. Formalised yolk sac antigen in early diagnosis of Legionnaires' disease caused by Legionella pneumophila serogroup 1.

3. Proximity of the home to a cooling tower and risk of non-outbreak Legionnaires' disease.

4. Legionella infections in Scotland.

Review 5. Legionella and Legionnaires' disease: 25 years of investigation.

6. Oropharyngeal colonization with Legionella pneumophila.