| Literature DB >> 7042745 |
B J Beaty, J Casals, K L Brown, C B Gundersen, D Nelson, J T McPherson, W H Thompson.
Abstract
A clinically relevant indirect fluorescent-antibody technique (IFA) was developed for the serological diagnosis of La Crosse virus infections. The IFA (67%) was as sensitive as the hemagglutination inhibition (58%) and neutralization (58%) tests in the detection of antibodies in acute-phase specimens. Immunoglobulin M antibodies were detected by the IFA test in 48% (11 of 23) of these specimens. Diagnostically significant increases in IFA titer were detected in 86% (19 of 22) of the paired samples. Antibodies were detectable in some patients 7 years after infection; however, the IFA test was not as sensitive as the other two tests in the detection of previous infections.Entities:
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Year: 1982 PMID： 7042745 PMCID： PMC272112 DOI： 10.1128/jcm.15.3.429-434.1982
Source DB: PubMed Journal: J Clin Microbiol ISSN： 0095-1137 Impact factor: 5.948