Literature DB >> 7042613

Ultrastructural features of the multiplication of human and murine leprosy bacilli in macrophages of nude mice.

Y Fukunishi, S Okada, M Nishiura, K Kohsaka.   

Abstract

Ultrastructural features of the growth of M. leprae and M. lepraemurium in nude mouse macrophages were studied by ultrathin sectioning and freeze-etching. In nude mouse macrophages, M. leprae produced spherical droplets (foamy structures) similar to those in human lepra cells. On the other hand, M. lepraemurium produced typical crystalline material in nude mouse macrophages, which is quite the same as that observed in the C3H strain mouse, Spherical droplets in the form of foamy structures seem to be made up of a specific substance produced by the multiplication of M. leprae in suitable host cells (human, nude mouse, and armadillo macrophages).

Entities:  

Mesh：

Year:  1982        PMID： 7042613

Source DB:  PubMed          Journal:  Int J Lepr Other Mycobact Dis        ISSN： 0148-916X


  4 in total

Review 1.  Biological, chemical, immunological and staining properties of bacteria isolated from tissues of leprosy patients.

Authors:  C Cocito; J Delville
Journal:  Eur J Epidemiol       Date:  1985-09       Impact factor: 8.082

2.  Study on the micromorphology of Mycobacterium leprae.

Authors:  G D Burchard; M Bierther
Journal:  Arch Dermatol Res       Date:  1985       Impact factor: 3.017

3.  Activities of fluoroquinolone, macrolide, and aminoglycoside drugs combined with inhibitors of glycosylation and fatty acid and peptide biosynthesis against Mycobacterium avium.

Authors:  W W Barrow; E L Wright; K S Goh; N Rastogi
Journal:  Antimicrob Agents Chemother       Date:  1993-04       Impact factor: 5.191

4.  Modified lymphocyte response to mitogens after intraperitoneal injection of glycopeptidolipid antigens from Mycobacterium avium complex.

Authors:  P E Brownback; W W Barrow
Journal:  Infect Immun       Date:  1988-05       Impact factor: 3.441
  4 in total

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