Literature DB >> 7041946

Expression of Ia antigen on epidermal keratinocytes is a consequence of cellular immunity.

A J Suitters, I A Lampert.   

Abstract

Ia antigen is seen in the normal epidermis only in Langerhans cells. However, when there is damage to the epidermis induced by cellular immunity Ia is expressed in the keratinocytes. This phenomenon is not seen in trauma or chemical inflammation. It is suggested that the expression of Ia in keratinocytes is due to cellular immunity possibly due to a lymphokine.

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Year:  1982        PMID： 7041946      PMCID： PMC2040611     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN： 0007-1021


  19 in total

1.  Identification of Ia glycoproteins in rat thymus and purification from rat spleen.

Authors:  W R McMaster; A F Williams
Journal:  Eur J Immunol       Date:  1979-06       Impact factor: 5.532

2.  The disappearance and regeneration of Langerhans cells following epidermal injury.

Authors:  R J Lessard; K Wolff; R K Winkelmann
Journal:  J Invest Dermatol       Date:  1968-02       Impact factor: 8.551

3.  Lymphocyte differentiation and major histocompatibility complex antigen expression in the embryonic thymus.

Authors:  E J Jenkinson; J J Owen; R Aspinall
Journal:  Nature       Date:  1980-03-13       Impact factor: 49.962

4.  The H-2 major histocompatibility complex and the I immune response region: genetic variation, function, and organization.

Authors:  D C Shreffler; C S David
Journal:  Adv Immunol       Date:  1975       Impact factor: 3.543

Review 5.  The immune response genes of the major histocompatibility complex.

Authors:  B Benacerraf; R N Germain
Journal:  Immunol Rev       Date:  1978       Impact factor: 12.988

Review 6.  Genetic and functional analysis of the Ia antigens: their possible role in regulating the immune response.

Authors:  H O McDevitt; T L Delovitch; J L Press; D B Murphy
Journal:  Transplant Rev       Date:  1976

7.  Expression of Ia-like antigens on cultured human malignant melanoma cell lines.

Authors:  R J Winchester; C Y Wang; A Gibofsky; H G Kunkel; K O Lloyd; L J Old
Journal:  Proc Natl Acad Sci U S A       Date:  1978-12       Impact factor: 11.205

8.  Regulation of macrophage populations. I. Preferential induction of Ia-rich peritoneal exudates by immunologic stimuli.

Authors:  D I Beller; J M Kiely; E R Unanue
Journal:  J Immunol       Date:  1980-03       Impact factor: 5.422

9.  Function of macrophages in antigen recognition by guinea pig T lymphocytes. I. Requirement for histocompatible macrophages and lymphocytes.

Authors:  A S Rosenthal; E M Shevach
Journal:  J Exp Med       Date:  1973-11-01       Impact factor: 14.307

10.  Ia determinants on stimulated human T lymphocytes. Occurrence on mitogen- and antigen-activated T cells.

Authors:  H S Ko; S M Fu; R J Winchester; D T Yu; H G Kunkel
Journal:  J Exp Med       Date:  1979-08-01       Impact factor: 14.307
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  20 in total

1.  Epidermal keratinocyte Ia expression, Langerhans cell hyperplasia and lymphocytic infiltration in skin lesions of leprosy.

Authors:  T H Rea; J Y Shen; R L Modlin
Journal:  Clin Exp Immunol       Date:  1986-08       Impact factor: 4.330

2.  Immunohistological evidence of lymphokine production and lymphocyte activation antigens in tuberculin reactions.

Authors:  M A Fullmer; J Y Shen; R L Modlin; T H Rea
Journal:  Clin Exp Immunol       Date:  1987-02       Impact factor: 4.330

3.  Induction of Thy-1 antigen on murine keratinocytes.

Authors:  A Scheynius; L Klareskog; R Holmdahl; P Larsson
Journal:  Immunology       Date:  1986-03       Impact factor: 7.397

4.  Class II antigen (HLA-DR) expression by intestinal epithelial cells in inflammatory diseases of colon.

Authors:  G B McDonald; D P Jewell
Journal:  J Clin Pathol       Date:  1987-03       Impact factor: 3.411

5.  Immunocytochemical analysis of HLA class II (DR) antigens in liver disease in man.

Authors:  C Barbatis; P Kelly; J Greveson; A Heryet; J O McGee
Journal:  J Clin Pathol       Date:  1987-08       Impact factor: 3.411

6.  Lymphocytic infiltration and HLA-DR expression of salivary glands in bone marrow transplant recipients: a prospective study.

Authors:  G Lindahl; B Lönnquist; E Hedfors
Journal:  Clin Exp Immunol       Date:  1988-05       Impact factor: 4.330

Review 7.  Cutaneous graft versus host disease.

Authors:  J I Harper
Journal:  Br Med J (Clin Res Ed)       Date:  1987-08-15

8.  Effects of interferon-gamma treatment on the cutaneous DTH reaction in rats.

Authors:  C Skoglund; A Scheynius
Journal:  Arch Dermatol Res       Date:  1990       Impact factor: 3.017

9.  Expression of MHC class II antigens on bile duct epithelium in experimental graft versus host disease.

Authors:  L Takács; B Szende; A Rot; T Diamanstein
Journal:  Clin Exp Immunol       Date:  1985-06       Impact factor: 4.330

10.  Expression of HLA-DR antigens by colonic epithelium in inflammatory bowel disease.

Authors:  W S Selby; G Janossy; D Y Mason; D P Jewell
Journal:  Clin Exp Immunol       Date:  1983-09       Impact factor: 4.330
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