| Literature DB >> 7038625 |
Abstract
The specificity of the lysosomal acid RNase [Saha, B.K., Graham, M.Y. and Schlessinger, D. (1979). J. Biol. Chem. 5951-5957] has been determined by 5'-end labeling and sequencing gel electrophoresis of rRNA. The enzyme has a predilection for the dinucleotide sequence ...NU..., which is cleaved into ...Np and HOU.... Sequences AU and GU sequences is enhanced by the presence of adjacent purine residues. The specificity remains unaltered after partial denaturation of the RNA.Entities:
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Year: 1982 PMID： 7038625 PMCID： PMC326163 DOI： 10.1093/nar/10.2.645
Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971