Literature DB >> 7038479

Genome organization and ploidy number in Trypanosoma cruzi.

C Castro, S P Craig, M Castañeda.   

Abstract

Trypanosoma cruzi total DNA was analyzed by DNA:DNA reassociation kinetics. The nonlinear least-squares computer solution could reasonably be fitted to three second-order kinetic components. The highly repetitive, middle repetitive, and single copy components comprised 9, 35 and 49% of the genome, respectively. The single copy sequences showed a kinetic complexity of approximately 4 times that of Escherichia coli and of some 11,000 average-sized structural genes. The repetitive sequences (about 6900) presented the long-period pattern of interspersion with a modal length of 7800 bases. The kinetic complexity of total DNA was compatible with a value of at least a diploid genome per cell.

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Year:  1981        PMID： 7038479     DOI： 10.1016/0166-6851(81)90060-8

Source DB:  PubMed          Journal:  Mol Biochem Parasitol        ISSN： 0166-6851            Impact factor:   1.759


  8 in total

Review 1.  Repetitive elements in genomes of parasitic protozoa.

Authors:  Bill Wickstead; Klaus Ersfeld; Keith Gull
Journal:  Microbiol Mol Biol Rev       Date:  2003-09       Impact factor: 11.056

Review 2.  Molecular diagnosis of parasites.

Authors:  V M Nantulya
Journal:  Experientia       Date:  1991-02-15

3.  Genomic variation of Trypanosoma cruzi: involvement of multicopy genes.

Authors:  W Wagner; M So
Journal:  Infect Immun       Date:  1990-10       Impact factor: 3.441

4.  Minichromosomal repetitive DNA in Trypanosoma cruzi: its use in a high-sensitivity parasite detection assay.

Authors:  A Gonzalez; E Prediger; M E Huecas; N Nogueira; P M Lizardi
Journal:  Proc Natl Acad Sci U S A       Date:  1984-06       Impact factor: 11.205

5.  Serine proteases from nematode and protozoan parasites: isolation of sequence homologs using generic molecular probes.

Authors:  J A Sakanari; C E Staunton; A E Eakin; C S Craik; J H McKerrow
Journal:  Proc Natl Acad Sci U S A       Date:  1989-07       Impact factor: 11.205

6.  New Trypanosoma cruzi repeated element that shows site specificity for insertion.

Authors:  Renata T Souza; Márcia R M Santos; Fábio M Lima; Najib M El-Sayed; Peter J Myler; Jeronimo C Ruiz; José Franco da Silveira
Journal:  Eukaryot Cell       Date:  2007-05-25

7.  The genomic organization and transcription of the ubiquitin genes of Trypanosoma cruzi.

Authors:  J Swindle; J Ajioka; H Eisen; B Sanwal; C Jacquemot; Z Browder; G Buck
Journal:  EMBO J       Date:  1988-04       Impact factor: 11.598

8.  Genome size, karyotype polymorphism and chromosomal evolution in Trypanosoma cruzi.

Authors:  Renata T Souza; Fábio M Lima; Roberto Moraes Barros; Danielle R Cortez; Michele F Santos; Esteban M Cordero; Jeronimo Conceiçao Ruiz; Samuel Goldenberg; Marta M G Teixeira; José Franco da Silveira
Journal:  PLoS One       Date:  2011-08-12       Impact factor: 3.240
  8 in total

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