Literature DB >> 7038463

Mutagenicity of styrene in the Salmonella typhimurium test system.

C de Meester, M Duverger-van Bogaert, M Lambotte-Vandepaer, M Mercier, F Poncelet.   

Abstract

The mutagenic activity of styrene was investigated by incubating the strains of Salmonella typhimurium in gaseous atmospheres. The sensitive strains were TA1530, TA1535 and TA100. In that method, styrene regularly showed a mutagenic activity in the presence of a fortified liver post-mitochondrial fraction. The mutagenic activity remained weak. Moreover, it seemed that a volatile mutagenic intermediate was formed metabolically during the assays; its identity remains unknown.

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Year:  1981        PMID: 7038463     DOI: 10.1016/0165-1218(81)90066-5

Source DB:  PubMed          Journal:  Mutat Res        ISSN: 0027-5107            Impact factor:   2.433


  2 in total

Review 1.  Critical review of styrene genotoxicity focused on the mutagenicity/clastogenicity literature and using current organization of economic cooperation and development guidance.

Authors:  Martha M Moore; Lynn H Pottenger; Tamara House-Knight
Journal:  Environ Mol Mutagen       Date:  2019-03-13       Impact factor: 3.216

2.  Biological monitoring of styrene in the reinforced plastics industry in Emilia Romagna, Italy.

Authors:  C Galassi; M Kogevinas; G Ferro; M Biocca
Journal:  Int Arch Occup Environ Health       Date:  1993       Impact factor: 3.015

  2 in total

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