| Literature DB >> 7038399 |
Abstract
Starting with an E. coli merodiploid strain (rpoB+ (rifS)/rpoB- (rifR)) containing equal amounts of rifampicin-sensitive and resistant RNA polymerase activities, mutants were isolated that had a disproportionately high ratio of the rifampicin-resistant enzyme activity. With one strain it is shown that the mutation responsible for this phenotype is closely linked to the rifR (rpoB-) allele.Entities:
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Year: 1981 PMID: 7038399 DOI: 10.1007/bf00352530
Source DB: PubMed Journal: Mol Gen Genet ISSN: 0026-8925