Literature DB >> 7038136

A two-stage technique for excision and grafting of burn wounds.

G D Warden, J R Saffle, M Kravitz.   

Abstract

While the technique of early excision and grafting has many advantages in the treatment of thermal injuries, it is not without significant complications. Hemorrhage accompanying burn wound excision can be deceptively great, as can the metabolic stress of large surgical procedures performed in the postburn period. In an effort to minimize these complications, we have developed a two-stage technique for excision and grafting of burn wounds. This technique employs layered excision of eschar, followed by an overnight stabilization period for restoration of normal body temperature and blood volume. Continuous soaking of excised areas promotes hemostasis, and insures a viable base for autografting performed on the following day. During 1978-1979, 117 burn patients underwent 137 two-stage excision and grafting procedures. Mean graft size was 1,988 cm2. Eighty-two per cent of the patients had all necessary grafting performed in a single two-stage operation, including grafts as large as 5,700 cm2. No graft loss occurred as a result of graft hematoma formation. Mean blood loss calculated for each two-stage operation was 2,627 cc, one third of which resulted from the harvesting of autografts. Temperature decrease during surgery was also great, with significant hypothermia occurring in 51% of procedures exceeding 2 hours in length. We conclude that performing excision and grafting in two stages limits hemorrhage and heat loss from each individual surgery, thereby permitting the performance of larger procedures. Nonetheless, continued awareness of the magnitude of these complications remains an essential of successful excisional therapy.

Entities:  

Mesh:

Year:  1982        PMID: 7038136     DOI: 10.1097/00005373-198202000-00004

Source DB:  PubMed          Journal:  J Trauma        ISSN: 0022-5282


  12 in total

1.  The impact of operative time and hypothermia in acute burn surgery.

Authors:  N Ziolkowski; A D Rogers; W Xiong; B Hong; S Patel; B Trull; M G Jeschke
Journal:  Burns       Date:  2017-10-28       Impact factor: 2.744

2.  Cultured skin substitutes reduce donor skin harvesting for closure of excised, full-thickness burns.

Authors:  Steven T Boyce; Richard J Kagan; Kevin P Yakuboff; Nicholas A Meyer; Mary T Rieman; David G Greenhalgh; Glenn D Warden
Journal:  Ann Surg       Date:  2002-02       Impact factor: 12.969

3.  Randomized, Paired-Site Comparison of Autologous Engineered Skin Substitutes and Split-Thickness Skin Graft for Closure of Extensive, Full-Thickness Burns.

Authors:  Steven T Boyce; Peggy S Simpson; Mary T Rieman; Petra M Warner; Kevin P Yakuboff; J Kevin Bailey; Judith K Nelson; Laura A Fowler; Richard J Kagan
Journal:  J Burn Care Res       Date:  2017 Mar/Apr       Impact factor: 1.845

Review 4.  Anemia of thermal injury: combined acute blood loss anemia and anemia of critical illness.

Authors:  Joseph A Posluszny; Richard L Gamelli
Journal:  J Burn Care Res       Date:  2010 Mar-Apr       Impact factor: 1.845

5.  Morphogenesis and Biomechanics of Engineered Skin Cultured Under Uniaxial Strain.

Authors:  Britani N Blackstone; Heather M Powell
Journal:  Adv Wound Care (New Rochelle)       Date:  2012-04       Impact factor: 4.730

6.  Early burn wound excision significantly reduces blood loss.

Authors:  M H Desai; D N Herndon; L Broemeling; R E Barrow; R J Nichols; R L Rutan
Journal:  Ann Surg       Date:  1990-06       Impact factor: 12.969

7.  Comparative assessment of cultured skin substitutes and native skin autograft for treatment of full-thickness burns.

Authors:  S T Boyce; M J Goretsky; D G Greenhalgh; R J Kagan; M T Rieman; G D Warden
Journal:  Ann Surg       Date:  1995-12       Impact factor: 12.969

8.  Noncytotoxic combinations of topical antimicrobial agents for use with cultured skin substitutes.

Authors:  S T Boyce; G D Warden; I A Holder
Journal:  Antimicrob Agents Chemother       Date:  1995-06       Impact factor: 5.191

9.  Novel biodegradable sandwich-structured nanofibrous drug-eluting membranes for repair of infected wounds: an in vitro and in vivo study.

Authors:  Dave Wei-Chih Chen; Jun-Yi Liao; Shih-Jung Liu; Err-Cheng Chan
Journal:  Int J Nanomedicine       Date:  2012-02-13

10.  Synthesis and characterization of collagen/PLGA biodegradable skin scaffold fibers.

Authors:  Alireza Sadeghi-Avalshahr; Samira Nokhasteh; Amir Mahdi Molavi; Mohammad Khorsand-Ghayeni; Meysam Mahdavi-Shahri
Journal:  Regen Biomater       Date:  2017-09-25
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