| Literature DB >> 7038045 |
Abstract
An enzyme-linked immunosorbent assay (ELISA) was developed for detecting IgG antibodies to the Pitman Moore strain of rabies virus in sera from subjects immunised wih HDCS vaccine. End-point titres of antibody were determined using a pocket calculator preprogrammed to analyse absorbence values of test sera and negative controls. The assay was highly reproducible, and very close agreement was achieved when the results were compared with those of the mouse neutralization test. Rabies enzyme-linked immunosorbent assay is easy to perform, the results are obtained within 48 hours, and because it employs inactivated virus, the test can be used safely without special containment facilities.Entities:
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Year: 1982 PMID: 7038045 PMCID: PMC7166757 DOI: 10.1002/jmv.1890090107
Source DB: PubMed Journal: J Med Virol ISSN: 0146-6615 Impact factor: 2.327