| Literature DB >> 7037969 |
D McCarthy, D H Goddard, E J Holborow, A C Horsfall, P A Mumford, R N Maini.
Abstract
The reactivity of heat-aggregated IgG of known size, in the Raji cell assay, the C1q binding assay and the C1q solid phase radioimmunoassay as a function of concentration, has been investigated. Marked differences were found in the way that the three assays behave when the IgG concentration and aggregate size are varied. These findings indicate the pitfalls in attempting to express the results of immune complex assays performed on biological fluids in terms of equivalent concentrations of aggregated IgG.Entities:
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Year: 1981 PMID： 7037969 DOI： 10.1016/0022-1759(81)90291-x
Source DB: PubMed Journal: J Immunol Methods ISSN： 0022-1759 Impact factor: 2.303