| Literature DB >> 7037958 |
D E Briles, M Nahm, T N Marion, R M Perlmutter, J M Davie.
Abstract
Streptococcal group A carbohydrate, which elicits mouse antibody of primarily the IgM and IgG3 isotypes, is relatively nonimmunogenic in nu/nu or xid mice, and thus appears to be a type of TD-2 antigen. The TD-2 antigens described previously have been proteins that elicit IgG antibody primarily of the IgG1 and IgG2 isotypes. Our findings indicate that TD-2 properties may also be a characteristic of at least some carbohydrate antigens that can elicit IgG antibody predominantly of the IgG3 class.Entities:
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Year: 1982 PMID： 7037958
Source DB: PubMed Journal: J Immunol ISSN： 0022-1767 Impact factor: 5.422