Literature DB >> 70375

Radiation-released histamine in the rhesus monkey as modified by mast-cell depletion and antihistamine.

T F Doyle, T A Strike.   

Abstract

4000 rads of mixed gamma neutron radiation administered to rhesus monkeys released a significant amount of histamine into their circulation. When the monkeys were treated with a mast-cell histamine depleter (compound 48/80) for 4 days and then irradiated, no increase in circulating histamine was seen. When 48/80 was give 20 min after irradiation, only a slight increase in histamine was seen, indicating that 4000 rads had released most of the mast-cell histamine.

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Year:  1977        PMID： 70375     DOI： 10.1007/BF01945962

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  7 in total

1.  Observations on mast cell changes, histamine release and local tissue damage in rats following x-irradiation.

Authors:  H A VAN DEN BRENK
Journal:  Br J Exp Pathol       Date:  1958-08

2.  Elevation of circulating blood histamine in patients undergoing deep roentgen therapy.

Authors:  E C LASSER; K W STENSTROM
Journal:  Am J Roentgenol Radium Ther Nucl Med       Date:  1954-12

3.  Compound 48/80: a potent histamine liberator.

Authors:  W D M PATON
Journal:  Br J Pharmacol Chemother       Date:  1951-09

4.  Studies on histamine-metabolizing enzymes in intact animals. II.

Authors:  R W SCHAYER; J KENNEDY; R L SMILEY
Journal:  J Biol Chem       Date:  1953-12       Impact factor: 5.157

5.  Studies on histamine release and degradation in rhesus and squirrel monkeys.

Authors:  J H Peters; G R Gordon; S A Ferguson
Journal:  Life Sci       Date:  1967-06-01       Impact factor: 5.037

6.  The prevention of radiation-induced, early, transient incapacitation of monkeys by an antihistamine.

Authors:  T F Doyle; C R Curran; J E Turns; T A Strike
Journal:  Proc Soc Exp Biol Med       Date:  1974-03

7.  Effect of antihistamine on early transient incapacitation of monkeys subjected to 4000 rads of mixed gamma-neutron radiation.

Authors:  T F Doyle; J E Turns; T A Strike
Journal:  Aerosp Med       Date:  1971-04
  7 in total
  1 in total

1.  Effects of aminoguanidine on pre- and post-irradiation regional cerebral blood flow, systemic blood pressure and plasma histamine levels in the primate.

Authors:  L G Cockerham; G D Prell; T J Cerveny; M O'Brien; J D Hampton
Journal:  Agents Actions       Date:  1991-03
  1 in total

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