| Literature DB >> 70374 |
P S Skov, A Geisler, R Klysner, S Norn.
Abstract
Both isobutylmethylxanthine and theophylline increased the level cyclic AMP in the mast cell. Theophylline reduced the allergic histamine release, whereas isobutylmethylxynthine caused a pronounced potentiation of the histamine release. This indicates that the hypothesis of an inverse relationship between the level of cyclic AMP in mast cells and histamine release is too simple.Entities:
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Year: 1977 PMID： 70374 DOI： 10.1007/BF01951308
Source DB: PubMed Journal: Experientia ISSN： 0014-4754