Literature DB >> 7037389

Immunotoxicology in the pharmaceutical industry.

K C Norbury.   

Abstract

Development of an immunotoxicology program within the pharmaceutical industry is described. With few guidelines in the area and a multitude of factors to consider, a basic screen for evaluating immune competence in species routinely used in toxicologic studies has been proposed. The future of immunotoxicology depends upon the ability of the selected immune function tests to be predictive of human risk.

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Year:  1982        PMID: 7037389      PMCID: PMC1568893          DOI: 10.1289/ehp.824353

Source DB:  PubMed          Journal:  Environ Health Perspect        ISSN: 0091-6765            Impact factor:   9.031


  8 in total

Review 1.  Immune suppression as related to toxicology.

Authors:  J G Vos
Journal:  CRC Crit Rev Toxicol       Date:  1977-05

2.  Effects of environmental contaminants on the immune system.

Authors:  L D Koller
Journal:  Adv Vet Sci Comp Med       Date:  1979

3.  Simplified whole blood method for evaluating in vitro lymphocyte reactivity of laboratory animals.

Authors:  T Han; J Pauly
Journal:  Clin Exp Immunol       Date:  1972-05       Impact factor: 4.330

4.  The identification of contact allergens by animal assay. The guinea pig maximization test.

Authors:  B Magnusson; A M Kligman
Journal:  J Invest Dermatol       Date:  1969-03       Impact factor: 8.551

5.  Specific protein assay.

Authors:  R F Ritchie
Journal:  Fed Proc       Date:  1975-11

6.  Effects of aging on the differentiation and proliferation potentials of cells of the immune system.

Authors:  T Makinodan; W H Adler
Journal:  Fed Proc       Date:  1975-02

7.  Effect of uracil mustard and several antitumor drugs on the primary antibody response in rats and mice.

Authors:  H H Buskirk; J A Crim; H G Petering; K Merritt; A G Johnson
Journal:  J Natl Cancer Inst       Date:  1965-06       Impact factor: 13.506

8.  Mycoplasma neurolyticum: a potent mitogen for rat B lymphocytes.

Authors:  Y Naot; S Merchav; H Ginsburg
Journal:  Eur J Immunol       Date:  1979-03       Impact factor: 5.532

  8 in total

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