Literature DB >> 7037034

A controlled study of slow-release theophylline and aminophylline in patients with chronic bronchitis.

P F Jenkins, J P White, A J Jariwalla, G Anderson, I A Campbell.   

Abstract

Twenty patients with chronic bronchitis who were also receiving beta-agonist inhalers entered a single-blind cross-over study comparing slow-release aminophylline (Phyllocontin) 325 mg twice daily and slow-release theophylline (Rona-slophyllin) 250 mg twice daily with placebo. 16 subjects who completed the study showed no objective or subjective benefit with either active preparation. Eight of the 16 patients achieved plasma theophylline levels of greater than 10 micrograms/ml on each of the drugs but no benefit was found when this group was analysed separately.

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Year:  1982        PMID: 7037034

Source DB:  PubMed          Journal:  Br J Dis Chest        ISSN: 0007-0971


  4 in total

1.  Slow release theophyllines and chronic bronchitis.

Authors:  G M Cochrane
Journal:  Br Med J (Clin Res Ed)       Date:  1984-12-15

2.  Value of theophylline treatment in patients handicapped by chronic obstructive lung disease.

Authors:  S E McKay; C A Howie; A H Thomson; B Whiting; G J Addis
Journal:  Thorax       Date:  1993-03       Impact factor: 9.139

3.  Plasma theophylline concentrations, six minute walking distances, and breathlessness in patients with chronic airflow obstruction.

Authors:  W V Evans
Journal:  Br Med J (Clin Res Ed)       Date:  1984-12-15

4.  Methylxanthines for exacerbations of chronic obstructive pulmonary disease: meta-analysis of randomised trials.

Authors:  R Graham Barr; Brian H Rowe; Carlos A Camargo
Journal:  BMJ       Date:  2003-09-20
  4 in total

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