Treatment of chronic kidney transplant rejection with prostacyclin - reduction of platelet deposition in the transplant; prolongation of platelet survival and improvement of transplant function.

8 patients with chronic kidney transplant rejection were treated intravenously with prostacyclin during 5 days. This treatment seemed to have a beneficial effect as measured by platelet deposition in the transplant and prolongation of platelet survival. In the majority of cases the transplant function improved. A longer duration of this therapeutic effect could be a new way for the long-term treatment of chronic kidney transplant rejection.