Literature DB >> 7035370

Experimental Escherichia coli ascending pyelonephritis in rats: active peroral immunization with live Escherichia coli.

I Mattsby-Baltzer, L A Hanson, S Olling, B Kaijser.   

Abstract

Peroral immunization with a live strain of Escherichia coli O6K13H1 against experimental ascending pyelonephritis caused by the same strain was studied in rats, and the effect of immunization on antibody titers against the O and K antigens and lipid A was determined. Peroral immunization with live bacteria protected significantly against pyelonephritis. Sera collected 1 week after infection from the immunized group were increased in immunoglobulin G (IgG) anti-O6 and IgM anti-K13 in comparison with the nonimmunized group. The peroral immunization did not correspondingly affect the response to lipid A. In urine, there was an IgG antibody response to the O6 antigen. In bronchopulmonary secretion, IgM, IgG, and IgA antibodies to O6 were detected. Perorally immunized animals had significantly higher levels of IgG and IgA anti-O6 compared with the nonimmunized group 1 week after infection. Passive transfer of anti-lipid A did not increase resistance against pyelonephritis.

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Year:  1982        PMID： 7035370      PMCID： PMC351090          DOI： 10.1128/iai.35.2.647-653.1982

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  29 in total

1.  The cellular immune response in experimental Escherichia coli pyelonephritis in the rat.

Authors:  A G Spencer; A P Fairhead
Journal:  Nephron       Date:  1972       Impact factor: 2.847

2.  Protection against gram-negative infections with antiserum to lipid A from Salmonella minnesota R595.

Authors:  N A Mullan; P M Newsome; P G Cunnington; G H Palmer; M E Wilson
Journal:  Infect Immun       Date:  1974-12       Impact factor: 3.441

3.  Enzyme-linked immunosorbent assay, Elisa. 3. Quantitation of specific antibodies by enzyme-labeled anti-immunoglobulin in antigen-coated tubes.

Authors:  E Engvall; P Perlmann
Journal:  J Immunol       Date:  1972-07       Impact factor: 5.422

4.  Immunology of Escherichia coli: K antigen and its relation to urinary-tract infection.

Authors:  B Kaijser
Journal:  J Infect Dis       Date:  1973-06       Impact factor: 5.226

5.  Immunoglobulin synthesis in lower urinary tract infection.

Authors:  W L Hand; J W Smith; T E Miller; J A Barnett; J P Sanford
Journal:  J Lab Clin Med       Date:  1970-01

6.  The significance of urease in proteus pyelonephritis: a bacteriological study.

Authors:  D M MacLaren
Journal:  J Pathol Bacteriol       Date:  1968-07

7.  Serum and secretory immunoglobulins of the rat.

Authors:  T S Bistany; T B Tomasi
Journal:  Immunochemistry       Date:  1970-05

8.  Elevated urinary secretory IgA in children with urinary tract infection.

Authors:  D T Uehling; E R Steihm
Journal:  Pediatrics       Date:  1971-01       Impact factor: 7.124

9.  Local immune response in experimental pyelonephritis.

Authors:  J D Lehmann; J W Smith; T E Miller; J A Barnett; J P Sanford
Journal:  J Clin Invest       Date:  1969-11       Impact factor: 14.808

10.  Secretory IgA in urinary tract infections.

Authors:  D B Kaufman; R Katz; R M McIntosh
Journal:  Br Med J       Date:  1970-11-21
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  7 in total

1.  Antibody responses in the lower respiratory tract and male urogenital tract in humans after nasal and oral vaccination with cholera toxin B subunit.

Authors:  A Rudin; G C Riise; J Holmgren
Journal:  Infect Immun       Date:  1999-06       Impact factor: 3.441

2.  Localization of a domain in the FimH adhesin of Escherichia coli type 1 fimbriae capable of receptor recognition and use of a domain-specific antibody to confer protection against experimental urinary tract infection.

Authors:  K Thankavel; B Madison; T Ikeda; R Malaviya; A H Shah; P M Arumugam; S N Abraham
Journal:  J Clin Invest       Date:  1997-09-01       Impact factor: 14.808

3.  Urinary antibody response after immunisation with a vaccine against urinary tract infection.

Authors:  D Kruze; K Holzbecher; M Andrial; W Bossart
Journal:  Urol Res       Date:  1989

Review 4.  Immunotherapeutic advances in the treatment of gram-negative bacterial sepsis.

Authors:  D L Dunn
Journal:  World J Surg       Date:  1987-04       Impact factor: 3.352

Review 5.  Mechanisms of renal damage owing to infection.

Authors:  Timo Jahnukainen; Ming Chen; Gianni Celsi
Journal:  Pediatr Nephrol       Date:  2005-05-12       Impact factor: 3.714

6.  Local cellular immune response in ascending urinary tract infection: occurrence of T-cells, immunoglobulin-producing cells, and Ia-expressing cells in rat urinary tract tissue.

Authors:  E M Hjelm
Journal:  Infect Immun       Date:  1984-06       Impact factor: 3.441

7.  Serum antibodies against common antigens of bacterial lipopolysaccharides in healthy adults and in patients with multiple myeloma.

Authors:  C Stoll; I Schedel; D Peest
Journal:  Infection       Date:  1985 May-Jun       Impact factor: 3.553
  7 in total

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