Literature DB >> 7035335

A search for the Indianapolis-variant of human alcohol dehydrogenase in liver autposy samples from North Germany and Japan.

D P Agarwal, D Meier-Tackmann, S Harada, H W Goedde.   

Abstract

Human liver alcohol dehydrogenase (ADH) variants were screened in random autopsy specimens from 53 North German and 34 Japanese individuals. Based on pH-activity profile and electrophoretic pattern, only ADH2 and ADH3 variants were detected. In relatively fresh specimens, an "anodic band" or "pi-ADH" band was also observed. The recently reported new molecular forms collectively called "ADH Indianapolis" (Bosron et al. 1980) could not be demonstrated and therefore may be confined hitherto only to the American black population.

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Year:  1981        PMID： 7035335     DOI： 10.1007/bf00293070

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  13 in total

1.  Atypical human liver alcohol dehydrogenase.

Authors:  J P von Wartburg; P M Schürch
Journal:  Ann N Y Acad Sci       Date:  1968-07-31       Impact factor: 5.691

2.  Alcohol dehydrogenase isozymes in adult human stomach and liver: evidence for activity of the ADH 3 locus.

Authors:  M Smith; D A Hopkinson; H Harris
Journal:  Ann Hum Genet       Date:  1972-03       Impact factor: 1.670

3.  An atypical human alcohol dehydrogenase.

Authors:  J P von Wartburg; J Papenberg; H Aebi
Journal:  Can J Biochem       Date:  1965-07

4.  Liver alcohol dehydrogenase in a Japanese population.

Authors:  M Fukui; C Wakasugi
Journal:  Nihon Hoigaku Zasshi       Date:  1972-01

5.  Developmental changes and polymorphism in human alcohol dehydrogenase.

Authors:  M Smith; D A Hopkinson; H Harris
Journal:  Ann Hum Genet       Date:  1971-02       Impact factor: 1.670

6.  Heterogeneity and new molecular forms of human liver alcohol dehydrogenase.

Authors:  W F Bosron; T K Li; B L Vallee
Journal:  Biochem Biophys Res Commun       Date:  1979-12-28       Impact factor: 3.575

7.  Liver alcohol dehydrogenase and aldehyde dehydrogenase in the Japanese: isozyme variation and its possible role in alcohol intoxication.

Authors:  S Harada; S Misawa; D P Agarwal; H W Goedde
Journal:  Am J Hum Genet       Date:  1980-01       Impact factor: 11.025

8.  Liver alcohol dehydrogenase in Japanese: high population frequency of atypical form and its possible role in alcohol sensitivity.

Authors:  G Stamatoyannopoulos; S H Chen; M Fukui
Journal:  Am J Hum Genet       Date:  1975-11       Impact factor: 11.025

9.  New molecular forms of human liver alcohol dehydrogenase: isolation and characterization of ADHIndianapolis.

Authors:  W F Bosron; T K Li; B L Vallee
Journal:  Proc Natl Acad Sci U S A       Date:  1980-10       Impact factor: 11.205

10.  Isolation of pi-alcohol dehydrogenase of human liver: is it a determinant of alcoholism?

Authors:  T K Li; W F Bosron; W P Dafeldecker; L G Lange; B L Vallee
Journal:  Proc Natl Acad Sci U S A       Date:  1977-10       Impact factor: 11.205
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