Literature DB >> 7035146

Regulation of 25 hydroxyvitamin D3 1-hydroxylase in serum-free monolayer culture of mouse kidney.

M Fukase, S J Birge, L Rifas, L V Avioli, L R Chase.   

Abstract

Primary monolayer cultures of cells from normal mouse kidney were initiated and maintained in serum-free medium supplemented with insulin, transferrin and prostaglandin E1. Renal epithelial cells grow to confluence without detectable growth of fibroblasts. These cells contain an active 25(OH)D3 1-hydroxylase with half-maximal formation of 1,25(OH)2D3 achieved at a substrate concentration of 13.3 nM. Activity of this enzyme is increased by low calcium medium or parathyroid hormone and decreased by high calcium medium, high phosphate medium or 1,25(OH)2D3.

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Year:  1982        PMID： 7035146     DOI： 10.1210/endo-110-3-1073

Source DB:  PubMed          Journal:  Endocrinology        ISSN： 0013-7227            Impact factor:   4.736


  10 in total

Review 1.  Clinical impact of bone and calcium metabolism changes in sarcoidosis.

Authors:  G Rizzato
Journal:  Thorax       Date:  1998-05       Impact factor: 9.139

2.  1,25-Dihydroxyvitamin D3 production by human keratinocytes. Kinetics and regulation.

Authors:  D D Bikle; M K Nemanic; E Gee; P Elias
Journal:  J Clin Invest       Date:  1986-08       Impact factor: 14.808

3.  Role of protein kinase C in parathyroid hormone stimulation of renal 1,25-dihydroxyvitamin D3 secretion.

Authors:  M Janulis; V Tembe; M J Favus
Journal:  J Clin Invest       Date:  1992-12       Impact factor: 14.808

4.  Local action of phosphate depletion and insulin-like growth factor 1 on in vitro production of 1,25-dihydroxyvitamin D by cultured mammalian kidney cells.

Authors:  L Condamine; C Menaa; F Vrtovsnik; F Vztovsnik; G Friedlander; M Garabédian
Journal:  J Clin Invest       Date:  1994-10       Impact factor: 14.808

5.  Evidence that calcitonin plays a role in the postnatal increase of serum 1 alpha,25-dihydroxyvitamin D.

Authors:  T Nishioka; T Yasuda; H Niimi; H Nakajima
Journal:  Eur J Pediatr       Date:  1988-02       Impact factor: 3.183

6.  Abnormal parathyroid hormone stimulation of 25-hydroxyvitamin D-1 alpha-hydroxylase activity in the hypophosphatemic mouse. Evidence for a generalized defect of vitamin D metabolism.

Authors:  T Nesbitt; M K Drezner; B Lobaugh
Journal:  J Clin Invest       Date:  1986-01       Impact factor: 14.808

7.  Simulated acidosis does not impair 1,25-dihydroxyvitamin D3 production by cultured kidney cells.

Authors:  J Cunningham; G Griffin; L V Avioli
Journal:  Calcif Tissue Int       Date:  1987-12       Impact factor: 4.333

Review 8.  Phosphate as a Signaling Molecule.

Authors:  Kittrawee Kritmetapak; Rajiv Kumar
Journal:  Calcif Tissue Int       Date:  2019-11-25       Impact factor: 4.333

9.  Regulation of CYP27B1 mRNA Expression in Primary Human Osteoblasts.

Authors:  K van der Meijden; H W van Essen; F W Bloemers; E A J M Schulten; P Lips; N Bravenboer
Journal:  Calcif Tissue Int       Date:  2016-03-25       Impact factor: 4.333

10.  Characterization of 1 alpha-hydroxylation of vitamin D3 sterols by cultured alveolar macrophages from patients with sarcoidosis.

Authors:  J S Adams; M A Gacad
Journal:  J Exp Med       Date:  1985-04-01       Impact factor: 14.307
  10 in total

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