Literature DB >> 7034725

The effect of inorganic phosphate on the stability of some enzymes.

M Rippa, M Signorini, T Bellini.   

Abstract

In the presence of 5nM-P1, 6-phosphogluconate dehydrogenase from the yeast Candida utilis is more resistant to proteolysis and to the inactivating action of some chemical and physical agents. P1 also protects other enzymes against proteolysis. A hypothesis for the mechanism of the stabilizing action of P1 is advanced.

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Year:  1981        PMID： 7034725      PMCID： PMC1163190          DOI： 10.1042/bj1970747

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  9 in total

1.  THE UNFOLDING AND REFOLDING OF RIBONUCLEASE IN UREA SOLUTIONS. I. RATES AND EXTENTS OF PHYSICAL CHANGES.

Authors:  E A BARNARD
Journal:  J Mol Biol       Date:  1964-11       Impact factor: 5.469

2.  Effects of polyoxyanions on sulfhydryl group modification of thymidylate synthetase.

Authors:  C A Lewis; W A Munroe; R B Dunlap
Journal:  Biochemistry       Date:  1978-12-12       Impact factor: 3.162

3.  6-Phosphogluconate dehydrogenase from Candida utilis.

Authors:  M Rippa; M Signorini
Journal:  Methods Enzymol       Date:  1975       Impact factor: 1.600

4.  Calorimetry of alkaline phosphatase. Stability of the monomer and effect of metal ion and phosphate binding on dimer stability.

Authors:  J F Chlebowski; S Mabrey; M C Falk
Journal:  J Biol Chem       Date:  1979-07-10       Impact factor: 5.157

5.  Kinetics of reassociation and reactivation of pig-muscle lactic dehydrogenase after acid dissociation.

Authors:  R Rudolph; R Jaenicke
Journal:  Eur J Biochem       Date:  1976-04-01

6.  The active site of 6-phosphogluconate dehydrogenase. A phosphate binding site and its surroundings.

Authors:  M Rippa; M Signorini; T Bellini; F Dallocchio
Journal:  Arch Biochem Biophys       Date:  1978-08       Impact factor: 4.013

7.  The effects of phosphate on the structure and stability of the luciferases from Beneckea harveyi, Photobacterium fischeri, and Photobacterium phosphoreum.

Authors:  T F Holzman; T O Baldwin
Journal:  Biochem Biophys Res Commun       Date:  1980-06-30       Impact factor: 3.575

8.  The principles of enzyme stabilization. IV. Modification of 'key' functional groups in the tertiary structure of proteins.

Authors:  V P Torchilin; A V Maksimenko; V N Smirnov; I V Berezin; A M Klibanov; K Martinek
Journal:  Biochim Biophys Acta       Date:  1979-03-16

9.  Amino acid sequence around the pyridoxal 5'-phosphate binding sites of 6-phosphogluconate dehydrogenase.

Authors:  L Minchiotti; S Ronchi; M Rippa
Journal:  Biochim Biophys Acta       Date:  1981-01-15
  9 in total
  1 in total

1.  Non-enzymic protein phosphorylation. Phosphorylation of 6-phosphogluconate dehydrogenase by acyl phosphates.

Authors:  F Dallocchio; M Matteuzzi; T Bellini
Journal:  Biochem J       Date:  1982-05-01       Impact factor: 3.857
  1 in total

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