Literature DB >> 7033932

Biosynthesis and transport of yeast mitochondrial phenylalanyl-tRNA synthetase.

M Diatewa, A J Stahl.   

Abstract

The biosynthesis of yeast mitochondrial Phe-tRNA synthetase is studied in vivo. Antibodies against the enzyme are raised in rabbits. They precipitate two proteins in the post-ribosomal supernatant of the yeast cell homogenate. Immunoprecipitate analysis on SDS - gel electrophoresis shows that the two types of mitochondrial enzyme subunits with molecular weights of 57,000 and 72,000, respectively, are cytoplasmically synthesized as larger, individual precursors. Terminal extensions of the precursors prevent enzyme activity. Mitochondrial membranes linked protease(s) play(s) an active role in maturation.

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Year:  1981        PMID： 7033932      PMCID： PMC327604          DOI： 10.1093/nar/9.23.6293

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  28 in total

1.  Cell-free synthesis of leaf protein: Identification of an apparent precursor of the small subunit of ribulose-1,5-bisphosphate carboxylase.

Authors:  A R Cashmore; M K Broadhurst; R E Gray
Journal:  Proc Natl Acad Sci U S A       Date:  1978-02       Impact factor: 11.205

2.  Radioiodination of proteins in single polyacrylamide gel slices. Tryptic peptide analysis of all the major members of complex multicomponent systems using microgram quantities of total protein.

Authors:  J H Elder; R A Pickett; J Hampton; R A Lerner
Journal:  J Biol Chem       Date:  1977-09-25       Impact factor: 5.157

3.  Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane.

Authors:  G Fairbanks; T L Steck; D F Wallach
Journal:  Biochemistry       Date:  1971-06-22       Impact factor: 3.162

4.  Nuclear origin of specific yeast mitochondrial aminoacyl-tRNA synthetases.

Authors:  J M Schneller; C Schneller; R Martin; A J Stahl
Journal:  Nucleic Acids Res       Date:  1976-05       Impact factor: 16.971

5.  Cytoplasmically made subunits of yeast mitochondrial F1-ATPase and cytochrome c oxidase are synthesized as individual precursors, not as polyproteins.

Authors:  A S Lewin; I Gregor; T L Mason; N Nelson; G Schatz
Journal:  Proc Natl Acad Sci U S A       Date:  1980-07       Impact factor: 11.205

6.  The transport of proteins into yeast mitochondria. Kinetics and pools.

Authors:  I Z Ades; R A Butow
Journal:  J Biol Chem       Date:  1980-10-25       Impact factor: 5.157

7.  Translocation of delta-aminolevulinate synthase from the cytosol to the mitochondria and its regulation by hemin in the rat liver.

Authors:  K Yamauchi; N Hayashi; G Kikuchi
Journal:  J Biol Chem       Date:  1980-02-25       Impact factor: 5.157

8.  Cell-free synthesis of a putative precursor of mitochondrial aspartate aminotransferase with higher molecular weight.

Authors:  P Sonderegger; R Jaussi; P Christen
Journal:  Biochem Biophys Res Commun       Date:  1980-06-30       Impact factor: 3.575

9.  Physical and genetic organization of petite and grande yeast mitochondrial DNA. IV. In vivo transcription products of mitochondrial DNA and localization of 23 S ribosomal RNA in petite mutants of saccharomyces cerevisiae.

Authors:  G Faye; C Kujawa; H Fukuhara
Journal:  J Mol Biol       Date:  1974-09-05       Impact factor: 5.469

10.  NH2-terminal amino acid sequences of precursor and mature forms of the ribulose-1,5-bisphosphate carboxylase small subunit from Chlamydomonas reinhardtii.

Authors:  G W Schmidt; A Devillers-Thiery; H Desruisseaux; G Blobel; N H Chua
Journal:  J Cell Biol       Date:  1979-12       Impact factor: 10.539
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  1 in total

Review 1.  Higher eukaryotic aminoacyl-tRNA synthetases in physiologic and pathologic states.

Authors:  C V Dang; C V Dang
Journal:  Mol Cell Biochem       Date:  1986-08       Impact factor: 3.396
  1 in total

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