Literature DB >> 7032900

The anaerobe-mediated mutagenicity of 2-nitrofluorene and 2-aminofluorene for Salmonella typhimurium.

G E Karpinsky, H S Rosenkranz.   

Abstract

Anaerobic bacteria (Bacteroides fragilis, B vulgatus, and B thetaiotaomicron) possess the enzymic ability to convert 2-nitrofluorene and 2-aminofluorene to substances mutagenic for Salmonella typhimurium. If it be assumed that the active intermediate for both chemicals is 2-hydroxylaminofluorene, then these bacteria possess reductive as well as oxidative capabilities.

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Year:  1980        PMID: 7032900     DOI: 10.1002/em.2860020305

Source DB:  PubMed          Journal:  Environ Mutagen        ISSN: 0192-2521


  3 in total

1.  Activation of cycasin to a mutagen for Saccharomyces cerevisiae by rat intestinal flora.

Authors:  V W Mayer; C J Goin
Journal:  Appl Environ Microbiol       Date:  1983-02       Impact factor: 4.792

2.  Purification and characterization of 1-nitropyrene nitroreductases from Bacteroides fragilis.

Authors:  T Kinouchi; Y Ohnishi
Journal:  Appl Environ Microbiol       Date:  1983-09       Impact factor: 4.792

Review 3.  In vivo metabolism and genotoxic effects of nitrated polycyclic aromatic hydrocarbons.

Authors:  L Möller
Journal:  Environ Health Perspect       Date:  1994-10       Impact factor: 9.031

  3 in total

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