Literature DB >> 7032773

Induction of leucocyte migration inhibitory factor (LIF) by stimulation with free hapten and water-insoluble epoxy resin.

Y Nakano, K Nakano, I Hara.   

Abstract

The indirect leucocyte migration inhibition test was applied to the contact sensitivity to a hapten (dinitrofluorobenzene, DNFB) and a water-insoluble epoxy resin (Araldite). Sensitized guinea-pig leucocytes were pulsed with DNFB, which was not conjugated to a carrier protein, or with Araldite which was made particulate by ultrasonication. When these pulsed leucocytes were incubated for 24 hr, they released significant amounts of leucocyte migration inhibitory factor (LIF). The optimal dose for pulse-stimulation was 10 microgram/ml. A correlation was observed between the degree of contact sensitivity and the production of LIF.

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Year:  1981        PMID： 7032773      PMCID： PMC1537392     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  11 in total

1.  Experimental sensitization with particular reference to picryl chloride.

Authors:  M W CHASE
Journal:  Int Arch Allergy Appl Immunol       Date:  1954

2.  Leukocyte migration in guinea pigs. II. Partial characterization of a leukocyte migration inhibitory factor distinct from macrophage migration inhibitory factor.

Authors:  P M Hoffman; D M Hanes; M Horsmanheimo; H H Fudenberg
Journal:  Cell Immunol       Date:  1977-04       Impact factor: 4.868

3.  Contact sensitivity in vitro. The production of macrophage inhibition factors from DNCB sensitized lymphocytes by subcellular organelles obtained from DNCB epidermal tissue.

Authors:  K Nishioka; H E Amos
Journal:  Immunology       Date:  1973-09       Impact factor: 7.397

4.  Studies on the contact sensitization of man with simple chemicals. I. Specific lymphocyte transformation in response to dinitrochlorobenzene sensitization.

Authors:  A E Miller; W R Levis
Journal:  J Invest Dermatol       Date:  1973-11       Impact factor: 8.551

5.  Lymphocyte transformation in contact sensitivity.

Authors:  A F Geczy; A Baumgarten
Journal:  Immunology       Date:  1970-08       Impact factor: 7.397

6.  Cell-mediated immunity to viruses measured by the indirect agarose technique of leukocyte migration inhibition.

Authors:  E M Anders; J B Natvig
Journal:  Cell Immunol       Date:  1976-12       Impact factor: 4.868

7.  Enhanced delayed hypersensitivity skin test reactivity with serial testing in healthy volunteers.

Authors:  E C Keystone; P Demerieux; D Gladman; L Poplonski; S Piper; R Buchanan
Journal:  Clin Exp Immunol       Date:  1980-04       Impact factor: 4.330

8.  Hapten-specific responses to contact sensitizers. Use of fluorodinitrobenzene to elicit migration inhibition and macrophage agglutination factors from lymph node cells of contact-sensitive guinea-pigs.

Authors:  H P Godfrey
Journal:  Immunology       Date:  1976-05       Impact factor: 7.397

9.  The two-step leukocyte migration inhibition factor (LIF) assay. Its use in evaluation of cellular immune function in patients with immunodeficiency diseases.

Authors:  S W Chapman; C H Kirkpatrick
Journal:  Cell Immunol       Date:  1978-04       Impact factor: 4.868

10.  In vitro studies of contact hypersensitivity. The effect of the haptens 2,4-dinitrochlorobenzene (DNCB) and 2,4-dinitrofluorobenzene (DNFB) and of hapten-protein conjugates on the migration of guinea-pig peritoneal exudate cells.

Authors:  J V Friend; M Lane
Journal:  Immunology       Date:  1973-11       Impact factor: 7.397
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