Literature DB >> 7032277

Distribution of blood group substances in normal human colon. Use of the unlabeled antibody (PAP) immunoperoxidase technic to identify A and B blood group substances.

E L Wiley, P Murphy, G Mendelsohn, J C Eggleston.   

Abstract

A modification of the unlabeled antibody immunoperoxidase technic, using human antisera to identify blood group substances A and B in normal human colon is described. Overall, staining for the blood group substances is strongest in the cecum and proximal colon; there is a progressive reduction of staining for the blood group substances in the distal colon with almost complete loss in the recto-sigmoid area. The blood group substances are present in epithelial cells and in epithelial mucin, the most intense positive staining often being located in the supranuclear, Golgi region of the cells.

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Year:  1981        PMID： 7032277     DOI： 10.1093/ajcp/76.6.806

Source DB:  PubMed          Journal:  Am J Clin Pathol        ISSN： 0002-9173            Impact factor:   2.493


  6 in total

1.  Development of a monoclonal antibody specifically reactive to gastrointestinal goblet cells.

Authors:  M Vecchi; S Sakamaki; B Diamond; A B Novikoff; P M Novikoff; K M Das
Journal:  Proc Natl Acad Sci U S A       Date:  1987-05       Impact factor: 11.205

2.  Expression of H type 1 antigen of ABO histo-blood group in normal colon and aberrant expressions of H type 2 and H type 3/4 antigens in colon cancer.

Authors:  N Fujitani; Y Liu; S Toda; K Shirouzu; T Okamura; H Kimura
Journal:  Glycoconj J       Date:  2000-05       Impact factor: 2.916

3.  Monoclonal antibody localization of A and B isoantigens in normal and malignant fixed human tissues.

Authors:  C Ernst; J Thurin; B Atkinson; H Wurzel; M Herlyn; N Stromberg; C Civin; H Koprowski
Journal:  Am J Pathol       Date:  1984-12       Impact factor: 4.307

4.  Glycoconjugates of the normal human colorectum: a lectin histochemical study.

Authors:  R F McMahon; M J Panesar; R W Stoddart
Journal:  Histochem J       Date:  1994-06

5.  Histochemical demonstration of sugar residues by lectin and immunocytochemical techniques for blood group antigens in human colon.

Authors:  J Nakayama; M Ota; T Honda; T Katsuyama
Journal:  Histochem J       Date:  1987-08

6.  Distribution and changes of glycoconjugates in rat colonic mucosa during development. A histochemical study using lectins.

Authors:  J Calderó; E Campo; X Calomarde; M Torra
Journal:  Histochemistry       Date:  1988
  6 in total

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