Literature DB >> 7030442

Propranolol in schizophrenia. I. Comparison of propranolol, chlorpromazine and placebo.

M Peet, M S Bethell, A Coates, A K Khamnee, P Hall, S J Cooper, D J King, R A Yates.   

Abstract

Fifty-three hospitalized chronic schizophrenic patients were treated with either propranolol, chlorpromazine or placebo in a double-blind randomized trials for up to three months. Propranolol in a usual dose of 640 mg/day, produced marked cardiovascular effects but no improvement in schizophrenic symptomatology relative to placebo. The effects of chlorpromazine were small and inconsistent.

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Year:  1981        PMID: 7030442     DOI: 10.1192/bjp.139.2.105

Source DB:  PubMed          Journal:  Br J Psychiatry        ISSN: 0007-1250            Impact factor:   9.319


  4 in total

Review 1.  [Use of certain cardiological drugs in the treatment of schizophrenia: review of the literature].

Authors:  P M Llorca; M A Wolf
Journal:  J Psychiatry Neurosci       Date:  1991-03       Impact factor: 6.186

2.  The effect of propranolol on CSF amine metabolites in psychiatric patients.

Authors:  D J King; S J Cooper; J Liddle
Journal:  Br J Clin Pharmacol       Date:  1983-03       Impact factor: 4.335

3.  Efficacy of propranolol on schizophrenic thought disorder.

Authors:  B B Sethi; S Dube
Journal:  Indian J Psychiatry       Date:  1981-10       Impact factor: 1.759

4.  A road less travelled by. A review lecture given to the Royal Irish Academy on the occasion of the Award of Merit and Silver Medal by the Consultative Committee for Pharmacology & Toxicology on 22 November 2001.

Authors:  David J King
Journal:  Ulster Med J       Date:  2003-11
  4 in total

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