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Literature DB >> 7030423

Semisynthesis and properties of some insulin analogs.

K Inouye, K Watanabe, Y Tochino, M Kobayashi, Y Shigeta.

Abstract

Entities: Gene

Mesh：

Substances：
Insulin
Receptor, Insulin

Year: 1981 PMID： 7030423 DOI： 10.1002/bip.1981.360200909

Source DB: PubMed Journal: Biopolymers ISSN： 0006-3525 Impact factor: 2.505

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Cited

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15 in total

1. Role of Proinsulin Self-Association in Mutant INS Gene-Induced Diabetes of Youth.

Authors: Jinhong Sun; Yi Xiong; Xin Li; Leena Haataja; Wei Chen; Saiful A Mir; Li Lv; Rachel Madley; Dennis Larkin; Arfah Anjum; Balamurugan Dhayalan; Nischay Rege; Nalinda P Wickramasinghe; Michael A Weiss; Pamela Itkin-Ansari; Randal J Kaufman; David A Ostrov; Peter Arvan; Ming Liu
Journal: Diabetes Date: 2020-03-05 Impact factor: 9.461

2. An examination of the role of insulin dimerisation and negative cooperativity using the biological properties of the despentapeptide and deshexapeptide insulins.

Authors: C S Cockram; R H Jones; P H Sonksen; M A Tatnell; S Q Zhu; G Dodson
Journal: Diabetologia Date: 1987-09 Impact factor: 10.122

3. Extending Halogen-based Medicinal Chemistry to Proteins: IODO-INSULIN AS A CASE STUDY.

Authors: Krystel El Hage; Vijay Pandyarajan; Nelson B Phillips; Brian J Smith; John G Menting; Jonathan Whittaker; Michael C Lawrence; Markus Meuwly; Michael A Weiss
Journal: J Biol Chem Date: 2016-11-14 Impact factor: 5.157

4. An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein.

Authors: Michael D Glidden; Khadijah Aldabbagh; Nelson B Phillips; Kelley Carr; Yen-Shan Chen; Jonathan Whittaker; Manijeh Phillips; Nalinda P Wickramasinghe; Nischay Rege; Mamuni Swain; Yi Peng; Yanwu Yang; Michael C Lawrence; Vivien C Yee; Faramarz Ismail-Beigi; Michael A Weiss
Journal: J Biol Chem Date: 2017-11-07 Impact factor: 5.157

10. Contribution of TyrB26 to the Function and Stability of Insulin: STRUCTURE-ACTIVITY RELATIONSHIPS AT A CONSERVED HORMONE-RECEPTOR INTERFACE.

Authors: Vijay Pandyarajan; Nelson B Phillips; Nischay Rege; Michael C Lawrence; Jonathan Whittaker; Michael A Weiss
Journal: J Biol Chem Date: 2016-04-26 Impact factor: 5.157

Semisynthesis and properties of some insulin analogs.

1. Role of Proinsulin Self-Association in Mutant INS Gene-Induced Diabetes of Youth.

2. An examination of the role of insulin dimerisation and negative cooperativity using the biological properties of the despentapeptide and deshexapeptide insulins.

3. Extending Halogen-based Medicinal Chemistry to Proteins: IODO-INSULIN AS A CASE STUDY.

4. An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein.

5. Contribution of the B16 and B26 tyrosine residues to the biological activity of insulin.

6. Identification of a mutant human insulin predicted to contain a serine-for-phenylalanine substitution.

7. Trypsin-catalysed formation of pig des-(23-63)-proinsulin from desoctapeptide-(B23-30)-insulin.

8. Biophysical optimization of a therapeutic protein by nonstandard mutagenesis: studies of an iodo-insulin derivative.

9. Insulin Wakayama: familial mutant insulin syndrome in Japan.

10. Contribution of TyrB26 to the Function and Stability of Insulin: STRUCTURE-ACTIVITY RELATIONSHIPS AT A CONSERVED HORMONE-RECEPTOR INTERFACE.