Papilledema in Behçet's syndrome.

Six patients with Behçet's syndrome (five male, one female) had intracranial hypertension diagnosed by elevated CSF pressure in the presence of normal or small ventricles. All six patients had headaches and papilledema. Histories included oral ulcers in 5 patients, genital ulcers in 3, uveitis in 1, arthralgia in 4, and thrombophlebitis in 3. One patient had obstruction of the superior vena cava. A filling defect in the superior sagittal sinus was shown in two patients by carotid angiography, and cerebral circulation time was prolonged in one patient. Papilledema and intracranial hypertension as a result of cerebral vein thrombosis can be initial manifestations of Behçet's syndrome. This has not been a well-recognized feature of the syndrome.