Literature DB >> 7026271

Flow microcalorimetric bioassay of polyene antibiotics: interaction with growing Saccharomyces cerevisiae.

A E Beezer, B Z Chowdhry.   

Abstract

Microcalorimetric investigation of the interaction of polyene antibiotics with mid-exponential cells of a growing culture of Saccharomyces cerevisiae has been used as the basis of a bioassay procedure. The assay is rapid, sensitive and reproducible. The results are compared to classical assays and potency ranking orders.

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Year:  1981        PMID: 7026271     DOI: 10.1007/bf01985663

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  9 in total

1.  Amino acid transport in yeast and effects of nystatin.

Authors:  E STACHIEWICZ; J H QUASTEL
Journal:  Can J Biochem Physiol       Date:  1963-02

2.  Combined microassay and determination of bioactivity of N-acetylnystatin.

Authors:  A E Beezer; B Z Chowdhry
Journal:  Talanta       Date:  1980-01       Impact factor: 6.057

3.  Unrealistic nature of the "MIC".

Authors:  S Selwyn
Journal:  J Antimicrob Chemother       Date:  1976-06       Impact factor: 5.790

4.  A comparative study of the microbiological assays currently available for nystatin raw material.

Authors:  R F Cosgrove; A E Beezer; R J Miles
Journal:  J Pharm Pharmacol       Date:  1979-03       Impact factor: 3.765

5.  Bioassay of nystatin bulk material by flow microcalorimetry.

Authors:  A E Beezer; R D Newell; J V Tyrrell
Journal:  Anal Chem       Date:  1977-01       Impact factor: 6.986

6.  Bioassay of antifungal antibiotics by flow microcalorimetry.

Authors:  A E Beezer; B Z Chowdhry; R D Newell; H J Tyrrell
Journal:  Anal Chem       Date:  1977-10       Impact factor: 6.986

Review 7.  Fungal sterols and the mode of action of the polyene antibiotics.

Authors:  J M Hamilton-Miller
Journal:  Adv Appl Microbiol       Date:  1974       Impact factor: 5.086

8.  The mode of action of polyene antibiotics; induced potassium leakage in Candida albicans.

Authors:  S M Hammond; P A Lambert; B N Kliger
Journal:  J Gen Microbiol       Date:  1974-04

9.  Application of flow microcalorimetry to analytical problems: the preparation, storage and assay of frozen inocula of Saccharomyces cerevisiae.

Authors:  A E Beezer; R D Newell; H J Tyrrell
Journal:  J Appl Bacteriol       Date:  1976-10
  9 in total
  1 in total

1.  Flow microcalorimetry as a tool for an improved analysis of antibiotic activity: the different stages of chloramphenicol action.

Authors:  D Krüger; P Giesbrecht
Journal:  Experientia       Date:  1989-04-15
  1 in total

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