Literature DB >> 7021140

Clonazepam (Rivotril) and carbamazepine (Tegretol) in psychomotor epilepsy: a randomized multicenter trial.

B Mikkelsen, P Berggreen, P Joensen, O Kristensen, O Køhler, B O Mikkelsen.   

Abstract

The antiepileptic properties of carbamazepine (Tegretol) and clonazepam (Rivotril) were compared in a double-blind randomized study comprising 36 patients with newly diagnosed, untreated psychomotor epilepsy (partial seizures with complex symptomatology). No significant differences were found between the two drugs during the 6 months of treatment. Measurements of concentrations in plasma confirmed that the patients exceeded the accepted lower limit for therapeutic range of the drugs.

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Year:  1981        PMID: 7021140     DOI: 10.1111/j.1528-1157.1981.tb06152.x

Source DB:  PubMed          Journal:  Epilepsia        ISSN: 0013-9580            Impact factor:   5.864


  9 in total

1.  New drugs for epilepsy: a review.

Authors:  S Verret
Journal:  Can Fam Physician       Date:  1983-01       Impact factor: 3.275

2.  Complex partial seizures: EEG foci and response to carbamazepine and sodium valproate.

Authors:  A K Gupta; P M Jeavons
Journal:  J Neurol Neurosurg Psychiatry       Date:  1985-10       Impact factor: 10.154

3.  The comparative efficacy of antiepileptic drugs for partial and tonic-clonic seizures.

Authors:  D Chadwick; D M Turnbull
Journal:  J Neurol Neurosurg Psychiatry       Date:  1985-11       Impact factor: 10.154

Review 4.  Clonazepam monotherapy for treating people with newly diagnosed epilepsy.

Authors:  Francesco Brigo; Stanley C Igwe; Nicola Luigi Bragazzi; Simona Lattanzi
Journal:  Cochrane Database Syst Rev       Date:  2022-02-21

Review 5.  Clinical pharmacokinetics and pharmacological effects of carbamazepine and carbamazepine-10,11-epoxide. An update.

Authors:  L Bertilsson; T Tomson
Journal:  Clin Pharmacokinet       Date:  1986 May-Jun       Impact factor: 6.447

Review 6.  Drug treatment of epilepsy. Outlines, criticism and perspectives.

Authors:  E Beghi; R Di Mascio; G Tognoni
Journal:  Drugs       Date:  1986-03       Impact factor: 9.546

Review 7.  Newer antiepileptic drugs. Towards an improved risk-benefit ratio.

Authors:  P N Patsalos; J W Sander
Journal:  Drug Saf       Date:  1994-07       Impact factor: 5.606

8.  Clonazepam monotherapy for treating people with newly diagnosed epilepsy.

Authors:  Francesco Brigo; Stanley C Igwe; Nicola Luigi Bragazzi; Simona Lattanzi
Journal:  Cochrane Database Syst Rev       Date:  2019-11-19

9.  Efficacy and safety of perampanel monotherapy in patients with focal-onset seizures with newly diagnosed epilepsy or recurrence of epilepsy after a period of remission: The open-label Study 342 (FREEDOM Study).

Authors:  Takamichi Yamamoto; Sung Chul Lim; Hirotomo Ninomiya; Yuichi Kubota; Won Chul Shin; Dong Wook Kim; Dong Jin Shin; Tohru Hoshida; Koji Iida; Taku Ochiai; Risa Matsunaga; Hiroyuki Higashiyama; Hidetaka Hiramatsu; Ji Hyun Kim
Journal:  Epilepsia Open       Date:  2020-06-07
  9 in total

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