Literature DB >> 7019725

Actions of cholera toxin and the prevention and treatment of cholera.

J Holmgren.   

Abstract

The drastic intestinal secretion of fluid and electrolytes that is characteristic of cholera is the result of reasonably well understood cellular and biochemical actions of the toxin secreted by Vibrio cholerae. Based on this understanding it is possible to devise new techniques for the treatment and prophylaxis of cholera to complement those based on fluid replacement therapy and sanitation.

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Year:  1981        PMID: 7019725     DOI: 10.1038/292413a0

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  149 in total

Review 1.  Entry of ricin and Shiga toxin into cells: molecular mechanisms and medical perspectives.

Authors:  K Sandvig; B van Deurs
Journal:  EMBO J       Date:  2000-11-15       Impact factor: 11.598

2.  Differential effect of cholera toxin on CD45RA+ and CD45RO+ T cells: specific inhibition of cytokine production but not proliferation of human naive T cells.

Authors:  K Eriksson; I Nordström; C Czerkinsky; J Holmgren
Journal:  Clin Exp Immunol       Date:  2000-08       Impact factor: 4.330

3.  Nasal and vaginal vaccinations have differential effects on antibody responses in vaginal and cervical secretions in humans.

Authors:  E L Johansson; L Wassén; J Holmgren; M Jertborn; A Rudin
Journal:  Infect Immun       Date:  2001-12       Impact factor: 3.441

4.  Antibody responses in the lower respiratory tract and male urogenital tract in humans after nasal and oral vaccination with cholera toxin B subunit.

Authors:  A Rudin; G C Riise; J Holmgren
Journal:  Infect Immun       Date:  1999-06       Impact factor: 3.441

5.  Mucosal immunogenicity of plant lectins in mice.

Authors:  E C Lavelle; G Grant; A Pusztai; U Pfüller; D T O'Hagan
Journal:  Immunology       Date:  2000-01       Impact factor: 7.397

6.  Involvement of antigen-presenting cells in the enhancement of the in vitro antibody responses by cholera toxin B subunit.

Authors:  Y Hirabayashi; S I Tamura; K Shimada; T Kurata
Journal:  Immunology       Date:  1992-03       Impact factor: 7.397

7.  Characterization of an anti-idiotypic MoAb bearing an internal image of the receptor-binding epitope of cholera toxin.

Authors:  G P Lucas; C L Cambiaso; J P Vaerman
Journal:  Clin Exp Immunol       Date:  1992-09       Impact factor: 4.330

8.  Activation of cholera toxin-specific T cells in vitro.

Authors:  C O Elson; S Solomon
Journal:  Infect Immun       Date:  1990-11       Impact factor: 3.441

Review 9.  Enteric nervous system. I. Physiology and pathophysiology of the intestinal tract.

Authors:  O Lundgren; J Svanvik; L Jivegård
Journal:  Dig Dis Sci       Date:  1989-02       Impact factor: 3.199

10.  Changes in intestinal fluid and mucosal immune responses to cholera toxin in Giardia muris infection and binding of cholera toxin to Giardia muris trophozoites.

Authors:  I Ljungström; J Holmgren; A M Svennerholm; A Ferrante
Journal:  Infect Immun       Date:  1985-10       Impact factor: 3.441

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