Literature DB >> 7018664

Metabolic formation of pyrenequinones as enhancing agents of mutagenicity in Salmonella.

H Okamoto, D Yoshida.   

Abstract

Pyrene and 1-methylpyrene in the pyrolysis product of cellulose, which enhances mutagenicity of 2-acetylaminofluorene, must be metabolized to expose enhancing activity. 1,6-Pyrenequinone and 1,8-pyrenequinone, having high enhancement activity, were first isolated and identified in the metabolites of pyrene by rat liver microsomal fraction.

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Year:  1981        PMID： 7018664     DOI： 10.1016/0304-3835(81)90110-5

Source DB:  PubMed          Journal:  Cancer Lett        ISSN： 0304-3835            Impact factor:   8.679


  3 in total

1.  Pyrene Metabolism in Crinipellis stipitaria: Identification of trans-4,5-Dihydro-4,5-Dihydroxypyrene and 1-Pyrenylsulfate in Strain JK364.

Authors:  B Lange; S Kremer; O Sterner; H Anke
Journal:  Appl Environ Microbiol       Date:  1994-10       Impact factor: 4.792

2.  Pyrene degradation by a Mycobacterium sp.: identification of ring oxidation and ring fission products.

Authors:  M A Heitkamp; J P Freeman; D W Miller; C E Cerniglia
Journal:  Appl Environ Microbiol       Date:  1988-10       Impact factor: 4.792

3.  A fungal P450 (CYP5136A3) capable of oxidizing polycyclic aromatic hydrocarbons and endocrine disrupting alkylphenols: role of Trp(129) and Leu(324).

Authors:  Khajamohiddin Syed; Aleksey Porollo; Ying Wai Lam; Jagjit S Yadav
Journal:  PLoS One       Date:  2011-12-02       Impact factor: 3.240
  3 in total

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