Less aggressive rejection therapy and low-dose corticosteroids leading to satisfactory cadaveric kidney graft survival and low morbidity rate.

A less aggressive approach in treatment of rejection crises has been introduced since January 1979. Findings in 39 patients demonstrate that rejection treatment can be started later and be applied with considerably less frequency without an increase in graft loss. A reduction of more than 50% in corticosteroid dosage applied within three months after transplantation seems to be possible, with a sharp decrease of morbidity rate.