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Literature DB >> 7017137

Captopril for refractory hypertension in patients with chronic renal failure and renal transplantation.

D V Hamilton, D B Evans, G Maidment, J S Pryor.

Abstract

The converting-enzyme inhibitor, captopril, was given to ten patients with refractory severe hypertension of renal origin: 6 patients had chronic renal failure, 3 patients had hypertension following renal transplantation, and one patient had hypertension and congestive cardiac failure. Control of blood pressure was achieved with doses from 78 to 400 mg/day. Severe hyperkalaemia occurred in one patients, ageusia (dose dependent) in another, and one patients withdrew from treatment because of nausea.

Entities: Chemical Disease Species

Mesh：

Substances：
Proline
Captopril

Year: 1981 PMID： 7017137 PMCID： PMC1438816

Source DB: PubMed Journal: J R Soc Med ISSN： 0141-0768 Impact factor: 5.344

19 in total

1. Interruption of the renin-angiotensin system in hypertensive patients by captopril induces sustained reduction in aldosterone secretion, potassium retention and natruiresis.

Authors: S A Atlas; D B Case; J E Sealey; J H Laragh; D N McKinstry
Journal: Hypertension Date: 1979 May-Jun Impact factor: 10.190

2. Long-term survival after renal transplantation in humans: (with special reference to histocompatibility matching, thymectomy, homograft glomerulonephritis, heterologous ALG , AND RECIPIENT MALIGNANCY).

Authors: T E Starzl; K A Porter; G Andres; C G Halgrimson; R Hurwitz; G Giles; P I Terasaki; I Penn; G T Schroter; J Lilly; S J Starkie; C W Putnam
Journal: Ann Surg Date: 1970-09 Impact factor: 12.969

Captopril for refractory hypertension in patients with chronic renal failure and renal transplantation.

1. Interruption of the renin-angiotensin system in hypertensive patients by captopril induces sustained reduction in aldosterone secretion, potassium retention and natruiresis.

2. Long-term survival after renal transplantation in humans: (with special reference to histocompatibility matching, thymectomy, homograft glomerulonephritis, heterologous ALG , AND RECIPIENT MALIGNANCY).

3. Nephrotic syndrome in patient on captopril.

4. Bilateral nephrectomy prior to renal transplantation.

5. Hyperkalemia resulting from captopril administration.

6. Minoxidil in refractory hypertension: benefits, risks.

7. Minoxidil in resistant hypertension.

8. Treatment of chronic congestive heart failure with captopril, an oral inhibitor of angiotensin-converting enzyme.

9. Mortality and morbidity in pretransplant bilateral nephrectomy: analysis of 305 cases.

10. Innappropriate renin secretion unmasked by captopril (SQ 14 225) in hypertension of chronic renal failure.

1. Repeated renal failure with use of captopril in a cystinotic renal allograft recipient.

Review 2. Cardiovascular drugs in children: angiotensin-converting enzyme inhibitors.

Review 3. Cardiovascular drugs in children. II. Angiotensin-converting enzyme inhibitors in pediatric patients.

4. Captopril in hypertension after renal transplantation.

5. Captopril for refractory hypertension in patients with impaired renal function.