Literature DB >> 7016082

Low density lipoproteins (LDL) are carriers for lipid peroxides and inhibit prostacyclin (PGI2) biosynthesis in arteries.

A Szczeklik, R J Gryglewski.   

Abstract

Serum lipid peroxides are concentrated in the LDL fraction. HDL and plasma proteins quench the interaction of LDL lipid peroxides with thiobarbituric acid. LDL inhibits prostacyclin biosynthesis both in incubated rat aortic slices and superfused bovine coronary arteries. It is proposed that atherogenic properties of LDL are associated with inactivation of arterial prostacyclin synthetase by lipid peroxides which are present in LDL.

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Year:  1980        PMID： 7016082

Source DB:  PubMed          Journal:  Artery        ISSN： 0098-6127


  4 in total

1.  Effects of mild physical exercise on serum lipoproteins and metabolites of arachidonic acid: a controlled randomised trial in middle aged men.

Authors:  R Rauramaa; J T Salonen; K Kukkonen-Harjula; K Seppänen; E Seppälä; H Vapaatalo; J K Huttunen
Journal:  Br Med J (Clin Res Ed)       Date:  1984-02-25

Review 2.  Animal products, diseases and drugs: a plea for better integration between agricultural sciences, human nutrition and human pharmacology.

Authors:  Olav A Christophersen; Anna Haug
Journal:  Lipids Health Dis       Date:  2011-01-20       Impact factor: 3.876

3.  Plasma factors influencing PGI2-like activity in patients with IgA nephropathy and Henoch-Schönlein purpura.

Authors:  S Túri; J Nagy; I Haszon; Z Havass; M Németh; C Bereczki
Journal:  Pediatr Nephrol       Date:  1989-01       Impact factor: 3.714

4.  Lipid peroxides and atherosclerosis.

Authors:  M D Stringer; P G Görög; A Freeman; V V Kakkar
Journal:  BMJ       Date:  1989-02-04
  4 in total

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