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Literature DB >> 7015285

The structure of the yeast ribosomal RNA genes. 3. Precise mapping of the 18 S and 25 S rRNA genes and structure of the adjacent regions.

A Bayev, O I Georgiev, A A Hadjiolov, N Nikolaev, K G Skryabin, V M Zakharyev.

Abstract

The 5'-terminal of Saccharomyces cerevisiae 18 S and 25 S rRNA are precisely mapped within the sequence of the rDNA repeating unit. The 3'-terminal of 25 S rRNA and 37 S pre-rRNA are located within a 548 bp segment of the rDNA repeating unit by the use of a DNA polymerase I extension technique. The analysis of the rDNA sequences at the structural gene boundaries reveals the presence of oligonucleotide repeats which may be involved in transcription or processing control mechanisms. The sequence of rDNA in the transcription termination region is determined and possible mechanisms shaping the 3'-end of 25 S rRNA are discussed.

Entities: Chemical Species

Mesh：

Substances：
RNA, Ribosomal

Year: 1981 PMID： 7015285 PMCID： PMC326712 DOI： 10.1093/nar/9.4.789

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

34 in total

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27 in total

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Journal: Mol Cell Biol Date: 1989-08 Impact factor: 4.272

5. Structural analysis of the human U3 ribonucleoprotein particle reveal a conserved sequence available for base pairing with pre-rRNA.

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