Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Adjuvant chemotherapy and immunotherapy for colorectal cancer: preliminary communication.

Literature DB >> 7014886

Adjuvant chemotherapy and immunotherapy for colorectal cancer: preliminary communication.

J Bancewicz, K C Calman, S G Macpherson, C S McArdle, J G McVie, M Soukop.

Abstract

Following surgical resection of Dukes' B or C colorectal cancers 72 patients have been randomly allocated to receive: 5-fluorouracil; or 5-fluorouracil and levamisole; or no treatment. Adjuvant treatment was continued for one year. 66 patients remain evaluable for up to 24 months. Preliminary results show no significant differences in survival or recurrence rates. Two patients receiving 5-fluorouracil and levamisole developed severe, but reversible, neutropenia. Other side effects were uncommon.

Entities: Chemical

Mesh：

Substances：
Levamisole
Fluorouracil

Year: 1980 PMID： 7014886 PMCID： PMC1437544 DOI： 10.1177/014107688007300308

Source DB: PubMed Journal: J R Soc Med ISSN： 0141-0768 Impact factor: 18.000

21 in total

1. Preoperative irradiation for carcinoma of the rectum and rectosigmoid colon: reportof a National Veterans Administration randomized study.

Authors: B Roswit; G A Higgins; R J Keehn
Journal: Cancer Date: 1975-06 Impact factor: 6.860

2. Rseults of surgery for gastric cancer and effect of adjuvant mitomycin C on cancer recurrence.

Authors: H Imanaga; H Nakazato
Journal: World J Surg Date: 1977-03 Impact factor: 3.352

3. Endocavitary irradiation in the curative treatment of early rectal cancers.

Authors: J Papillon
Journal: Dis Colon Rectum Date: 1974 Mar-Apr Impact factor: 4.585

4. FUDR as an adjuvant to surgery in cancer of the large bowel.

Authors: R W Dwight; E W Humphrey; G A Higgins; R J Keehn
Journal: J Surg Oncol Date: 1973 Impact factor: 3.454

5. Preoperative roentgen therapy for cancer of the rectum and rectosigmoid.

Authors: M W Stearns; M R Deddish; S H Quan; R H Leaming
Journal: Surg Gynecol Obstet Date: 1974-04

6. The use of triethylenethiophosphoramide as an adjuvant to the surgical treatment of colorectal carcinoma.

Authors: W D Holden; W J Dixon; J W Kuzma
Journal: Ann Surg Date: 1967-04 Impact factor: 12.969

7. Intrapleural B.C.G. immunostimulation in lung cancer.

Authors: M F McKneally; C M Maver; H W Kausel
Journal: Lancet Date: 1977-05-07 Impact factor: 79.321

8. Therapy of advanced colorectal cancer with a combination of 5-fluorouracil, methyl-1,3-cis(2-chlorethyl)-1-nitrosourea, and vincristine.

Authors: C G Moertel; A J Schutt; R G Hahn; R J Reitemeier
Journal: J Natl Cancer Inst Date: 1975-01 Impact factor: 13.506

Adjuvant chemotherapy and immunotherapy for colorectal cancer: preliminary communication.

1. Preoperative irradiation for carcinoma of the rectum and rectosigmoid colon: reportof a National Veterans Administration randomized study.

2. Rseults of surgery for gastric cancer and effect of adjuvant mitomycin C on cancer recurrence.

3. Endocavitary irradiation in the curative treatment of early rectal cancers.

4. FUDR as an adjuvant to surgery in cancer of the large bowel.

5. Preoperative roentgen therapy for cancer of the rectum and rectosigmoid.

6. The use of triethylenethiophosphoramide as an adjuvant to the surgical treatment of colorectal carcinoma.

7. Intrapleural B.C.G. immunostimulation in lung cancer.

8. Therapy of advanced colorectal cancer with a combination of 5-fluorouracil, methyl-1,3-cis(2-chlorethyl)-1-nitrosourea, and vincristine.

9. Adjuvant chemotherapy in the surgical treatment of large bowel cancer.

10. Complications of cancer immunotherapy with levamisole.

1. Adjuvant therapy for cancer of the colon.

Review 2. Levamisole/fluorouracil. A review of their pharmacology and adjuvant therapeutic use in colorectal cancer.

3. Levamisole and 5-fluorouracil therapy for resected colon cancer: a new indication.

4. Adjuvant therapy in colorectal cancer.

5. Late mortality and levamisole adjuvant therapy in colorectal cancer.