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Literature DB >> 7013253

Renin localization in segmental renal hypoplasia. Immunohistochemical demonstration in two cases.

D Amat, J P Camilleri, V N Phat, J Bariety, P Corvol, J Menard.

Abstract

The distribution of renin in two cases of segmental renal hypoplasia was investigated by immunofluorescence and the peroxidase anti-peroxidase (PAP) method using an anti-human renin antiserum. Renin-containing cells were found only in hypoplasic segments in the vicinity of altered glomeruli and small arteries. Well-preserved renal cortex and areas of chronic atrophic pyelonephritis failed to show any demonstrable site of renin production. Whatever is the mechanism of the disease, the characterization of large numbers of renin-containing cells in the affected kidney support a role for the renin-angiotensin system stimulation in this form of hypertension.

Entities: Disease Gene Species

Mesh：

Substances：
Renin

Year: 1981 PMID： 7013253 DOI： 10.1007/bf02215984

Source DB: PubMed Journal: Virchows Arch A Pathol Anat Histol ISSN： 0340-1227

15 in total

1. [SEGMENTARY HYPOPLASIA OF THE KIDNEY WITH ARTERIAL HYPERTENSION IN CHILDREN].

Authors: R HABIB; V COURTECUISSE; J EHRENSPERGER; P ROYER
Journal: Ann Pediatr (Paris) Date: 1965-04-02

2. The ask-upmark kidney. A congenital renal anomaly studied by micro-angiography and histology.

Authors: A LJUNGQVIST; C LAGERGREN
Journal: Acta Pathol Microbiol Scand Date: 1962

3. Hypertension in children with chronic pyelonephritis.

Authors: N H Holland; T Kotchen; D Bhathena
Journal: Kidney Int Suppl Date: 1975-09 Impact factor: 10.545

4. Plasma renin activity in segmental hypoplasia of the kidneys with hypertension.

Authors: C Godard; M B Vallotton; M Broyer
Journal: Nephron Date: 1973 Impact factor: 2.847

5. Unilateral renal hypoplasia with hypertension (Ask-Upmark kidney).

Authors: J B Rosenfeld; L Cohen; I Garty; M Ben-Bassat
Journal: Br Med J Date: 1973-04-28

6. The development and ultrastructure of the juxtaglomerular cell granule.

Authors: L Barajas
Journal: J Ultrastruct Res Date: 1966-06

7. Evidence for a renal vascular mechanism in renin release: new observations with graded stimulation by aortic constriction.

Authors: E H Blaine; J O Davis
Journal: Circ Res Date: 1971-05 Impact factor: 17.367

Review 4. Renal Hypoplasia, From Grossly Insufficient to Not Quite Enough: Consideration for Expanded Concepts Based Upon the Author's Perspective With Historical Review.

Authors: Stephen M Bonsib
Journal: Adv Anat Pathol Date: 2020-09 Impact factor: 4.571

4 in total

Renin localization in segmental renal hypoplasia. Immunohistochemical demonstration in two cases.

1. [SEGMENTARY HYPOPLASIA OF THE KIDNEY WITH ARTERIAL HYPERTENSION IN CHILDREN].

2. The ask-upmark kidney. A congenital renal anomaly studied by micro-angiography and histology.

3. Hypertension in children with chronic pyelonephritis.

4. Plasma renin activity in segmental hypoplasia of the kidneys with hypertension.

5. Unilateral renal hypoplasia with hypertension (Ask-Upmark kidney).

6. The development and ultrastructure of the juxtaglomerular cell granule.

7. Evidence for a renal vascular mechanism in renin release: new observations with graded stimulation by aortic constriction.

8. [Hypertension of the renal artery and its surgical therapy in childhood].

9. Use of a specific antiserum for renin detection in human kidney.

10. Unilateral renal hypoplasia with associated venous anomaly and hypertension. A study of the juxtaglomerular cells.

1. New monoclonal antibodies directed against human renin. Powerful tools for the investigation of the renin system.

2. An ultrastructural and immunocytochemical study of a renal carcinoma secreting inactive renin.

3. Renin in renal cell carcinoma--an immunocytochemical study using an antibody to pure human renin.

Review 4. Renal Hypoplasia, From Grossly Insufficient to Not Quite Enough: Consideration for Expanded Concepts Based Upon the Author's Perspective With Historical Review.