Literature DB >> 7011216

Lipid synthesis from the liver in patients with psoriasis.

G Mingrone, A V Greco, A Venier, E Peruzzi, F Serri.   

Abstract

In psoriatic patients with hyperlipidemia we studied the hepatic lipid synthesis from (1-(14)C)-acetate in human liver biopsy specimens in vitro by a thin-layer radio-chromatography. In psoriatics type IV (according to Fredrickson) a significant increase in (1-(14)C)-acetate hepatic incorporation especially into phospholipids (25%) and triglycerides (52%) was observed; in type IIb increased lipogenesis was phospholipids (24.5%), free cholesterol (44.4%) and triglycerides (29%). Abnormal lipid metabolism often coexists with glucose intolerance in psoriasis; no correlation between hyperinsulinemia and augmented (1-(14)C)-acetate incorporation into hepatic triglycerides was found.

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Year:  1980        PMID： 7011216     DOI： 10.1007/bf00404288

Source DB:  PubMed          Journal:  Arch Dermatol Res        ISSN： 0340-3696            Impact factor:   3.017


  16 in total

1.  A simple method for the isolation and purification of total lipides from animal tissues.

Authors:  J FOLCH; M LEES; G H SLOANE STANLEY
Journal:  J Biol Chem       Date:  1957-05       Impact factor: 5.157

2.  Immunoreactive insulin, glucose tolerance, and carbohydrate inducibility in types II, 3, IV, and V hyperlipoproteinemia.

Authors:  C J Glueck; R I Levy; D S Fredrickson
Journal:  Diabetes       Date:  1969-11       Impact factor: 9.461

3.  Coated charcoal immunoassay of insulin.

Authors:  V Herbert; K S Lau; C W Gottlieb; S J Bleicher
Journal:  J Clin Endocrinol Metab       Date:  1965-10       Impact factor: 5.958

4.  Lipid and carbohydrate abnormalities in patients with angiographically documented coronary artery disease.

Authors:  R A Heinle; R I Levy; D S Frederickson; R Gorlin
Journal:  Am J Cardiol       Date:  1969-08       Impact factor: 2.778

5.  Plasma-insulin in coronary heart-disease: response to oral and intravenous glucose and to tolbutamide.

Authors:  E A Nikkilä; T A Miettinen; M R Vesenne; R Pelkonen
Journal:  Lancet       Date:  1965-09-11       Impact factor: 79.321

6.  Complete separation of lipid classes on a single thin-layer plate.

Authors:  C P Freeman; D West
Journal:  J Lipid Res       Date:  1966-03       Impact factor: 5.922

7.  Serum lipids, intravenous glucose tolerance and their interrelation studied in ischaemic cardiovascular disease.

Authors:  L A Carlson; F Wahlberg
Journal:  Acta Med Scand       Date:  1966-09

8.  Cholesterol synthesis in the squirrel monkey: relative rates of synthesis in various tissues and mechanisms of control.

Authors:  J M Dietschy; J D Wilson
Journal:  J Clin Invest       Date:  1968-01       Impact factor: 14.808

9.  Serum lipids in patients with psoriasis.

Authors:  S Brenner; A Krakowski; O Levtov; D Heldenberg; B Werbin; I Tamir
Journal:  Dermatologica       Date:  1975

10.  The immediate effects of insulin and fructose on the metabolism of the perfused liver. Changes in lipoprotein secretion, fatty acid oxidation and esterification, lipogenesis and carbohydrate metabolism.

Authors:  D L Topping; P A Mayes
Journal:  Biochem J       Date:  1972-01       Impact factor: 3.857
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  1 in total

Review 1.  Lipid disturbances in psoriasis: an update.

Authors:  Aldona Pietrzak; Anna Michalak-Stoma; Grazyna Chodorowska; Jacek C Szepietowski
Journal:  Mediators Inflamm       Date:  2010-07-20       Impact factor: 4.711
  1 in total

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